1620408-96-9

Basic information

• Product Name: (R)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl ((benzyloxy)carbonyl)-L-leucinate
• Synonyms: (R)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl ((benzyloxy)carbonyl)-L-leucinate
• CAS NO: 1620408-96-9
• Molecular Weight: 601.868
• Mol File: 1620408-96-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl ((benzyloxy)carbonyl)-L-leucinate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl ((benzyloxy)carbonyl)-L-leucinate(1620408-96-9)
• EPA Substance Registry System: (R)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl ((benzyloxy)carbonyl)-L-leucinate(1620408-96-9)

Safety Data

• Hazardous Substances Data: 1620408-96-9(Hazardous Substances Data)

Upstream product

• 943346-53-0 N-methoxy-N-methyl dodecanamide 
• 106-33-2 ethyl laurate 
• 112-54-9 Dodecanal 
• 1620409-00-8 pentadec-2-yn-4-one 
• 1620408-77-6 (S)-pentadec-2-yn-4-ol 
• 1620409-09-7 (S)-pentadec-1-yn-4-ol 
• 76828-23-4 (S)-4-Hydroxypentadec-1-ene 
• 1620408-78-7 (S)-tert-butyldimethyl(pentadec-1-yn-4-yloxy)silane 
• 1620409-10-0 (S)-tert-butyl(henicos-7-yn-10-yloxy)dimethylsilane 
• 1620408-79-8 (S)-henicos-7-yn-10-ol 
• 1620408-99-2 (S,Z)-henicos-7-en-10-ol 
• 1620408-80-1 (S)-1-((2S,3R)-3-hexyloxiran-2-yl)tridecan-2-ol 
• 1620408-98-1 (2R,3S)-2-hexyl-3-((S)-2-(methoxymethoxy)tridecyl)oxirane 
• 1620408-81-2 (3S,4S)-3-hexyl-4-((S)-2-(methoxymethoxy)tridecyl)oxetan-2-one 

Downstream Products

• 1225451-00-2 (R)-1'-<((2''S,3''S)-3''-hexyl-4''-oxo-2''-oxetanyl)methyl>dodecyl (S)-N-formylleucinate 

Relevant articles and documents

Total synthesis of tetrahydrolipstatin and stereoisomers via a highly regio- and diastereoselective carbonylation of epoxyhomoallylic alcohols

A concise enantioselective synthesis of tetrahydrolipstatin (THL) and seven stereoisomers has been achieved. The synthesis of THL was accomplished in 10 steps and 31% overall yield from an achiral ynone. Key to the success of the approach is the use of a bimetallic [Lewis acid]+[Co(CO)4]- catalyst for a late-stage regioselective carbonylation of an enantiomerically pure cis-epoxide to a trans-β-lactone. The success of this route to THL and its stereoisomers also demonstrated the practicality of the carbonylation catalyst for complex molecule synthesis as well as its functional group compatibility.