162361-41-3

Basic information

• Product Name: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide
• Synonyms: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide
• CAS NO: 162361-41-3
• Molecular Formula: C21H35NO4
• Molecular Weight: 365.5069
• Mol File: 162361-41-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.088±0.06 g/cm3 (20 ºC 760 Torr)
• Solubility: Methanol; Dichloromethane; DMSO
• CAS DataBase Reference: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide(162361-41-3)
• EPA Substance Registry System: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide(162361-41-3)

Safety Data

• Hazardous Substances Data: 162361-41-3(Hazardous Substances Data)

Usage

Description

N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide is a complex organic compound that serves as a crucial intermediate in the synthesis of pharmaceuticals. It is characterized by its unique molecular structure, which includes a hydroxyl group, two hydroxymethyl groups, and an octylphenyl group attached to a propyl chain. This structure endows the compound with specific properties that make it valuable in the development of certain medications.

Uses

Used in Pharmaceutical Synthesis:
N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide is used as an intermediate in the synthesis of 1-Hydroxy Fingolimod Hydrochloride (H942605). N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide is an impurity of the drug Fingolimod (F805000, HCl salt), which is a novel immune modulator. Fingolimod has been shown to prolong allograft transplant survival in various models by inhibiting lymphocyte emigration from lymphoid organs, making it a valuable asset in the field of organ transplantation and immunology.
In the pharmaceutical industry, N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide plays a vital role in the development and production of Fingolimod, a drug with significant potential in improving the outcomes of allograft transplants and managing autoimmune diseases. Its unique chemical structure allows for the creation of compounds with specific biological activities, contributing to the advancement of medical treatments and therapies.