1624302-00-6

Basic information

• Product Name: 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate
• CAS NO: 1624302-00-6
• Molecular Weight: 315.367
• Mol File: 1624302-00-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate(1624302-00-6)
• EPA Substance Registry System: 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate(1624302-00-6)

Safety Data

• Hazardous Substances Data: 1624302-00-6(Hazardous Substances Data)

Usage

Molecular structure

A complex structure with a piperidine ring as the central core, featuring three carboxylate groups and multiple alkyl substituents.

Piperidine derivative

The compound is based on a piperidine ring, which is a six-membered heteroaromatic ring containing one nitrogen atom.

Alkyl substituents

The compound contains various alkyl groups, including a tert-butyl (-C(CH3)3), an ethyl (-CH2CH3), and a methyl (-CH3) group, which influence its steric properties and lipophilicity.

Pharmaceutical applications

Due to its unique structure and functional groups, 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate has potential uses in the pharmaceutical industry.

Medicinal chemistry

The compound may be used as a building block for the synthesis of novel drugs or pharmaceutical compounds, contributing to the development of new therapeutic agents.

Biological activity

The compound may exhibit biological activity, which could be relevant for its potential applications in medicine and drug development.

Further research needed

To fully understand the potential uses and properties of 1-tert-butyl 3-ethyl 3-methyl piperidine-1,3,3-tricarboxylate, additional research and testing are required.

Upstream product

• 148672-74-6 ethyl N-(t-butyloxycarbonyl)nipecotate 
• 79-22-1 methyl chloroformate 

Downstream Products

• 1245816-29-8 tert-butyl 2-oxa-6-azaspiro[3,5]nonane-6-carboxylate 

Relevant articles and documents

2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF

[Problem] A compound which is useful as an active ingredient of a pharmaceutical composition for treating storage dysfunctions, voiding dysfunctions, and lower urinary tract diseases is provided. [Means for Solution] The present inventors have found that a thiazole derivative having pyrazine-2-carbonylamino substituted at the 2-position is an excellent muscarinic M3 receptor positive allosteric modulator, and is useful as an agent for preventing and/or treating bladder or urinary tract diseases, related to bladder contraction by a muscarinic M3 receptor, thereby completing the present invention. The 2-acylaminothiazole derivative or a salt thereof of the present invention can be used as an agent for preventing and/or treating bladder or urinary tract diseases, related to bladder contraction by a muscarinic M3 receptor, for example, voiding dysfunctions such as underactive bladder.

Towards a new synthetic entry into the Iboga-alkaloid family

A novel retrosynthetic concept is presented that, in principle, allows access to many hitherto not accessible representatives of the Iboga-alkaloid family. The flexibility required by this approach is provided through a highly convergent assembly of the target, which allows for a control over the substitution pattern of the indole sub-system, as well as over the relative configuration of the aliphatic core of these alkaloids. The key step for the construction of the latter consists in an intramolecular nitrone-olehn 1,3-dipolar cycloaddition reaction of 26 to yield the crucial tricyclic isoxazolidine derivative 28.