163634-08-0

Basic information

• Product Name: Benzenepropanol,4-hydroxy-b-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3-methoxy-,(bS)-
• Synonyms: Benzenepropanol,4-hydroxy-b-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3-methoxy-,(E)-(+)-; (+)-Imperanene; (S)-Imperanene; Imperanene
• CAS NO: 163634-08-0
• Molecular Formula: C19H22 O5
• Molecular Weight: 330.381
• Mol File: 163634-08-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenepropanol,4-hydroxy-b-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3-methoxy-,(bS)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanol,4-hydroxy-b-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3-methoxy-,(bS)-(163634-08-0)
• EPA Substance Registry System: Benzenepropanol,4-hydroxy-b-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3-methoxy-,(bS)-(163634-08-0)

Safety Data

• Hazardous Substances Data: 163634-08-0(Hazardous Substances Data)

Upstream product

• 370878-64-1 CHCH₂CH₂C₆H₃OCH₃OSiC₄H₉(CH₃)2CHOCHC₆H₃OCH₃OSiC₄H₉(CH₃)2Si(CH₃)3 
• 431879-30-0 (3S)-(+)-1,4-bis[4-(tert-butyldiphenylsilanyloxy)-3-methoxyphenyl]-3-(tert-butyldiphenylsilanyl-oxymethyl)but-1-ene 
• 67-56-1 methanol 
• 347359-71-1 (7RS,8R,8'R)-4,4',7-trihydroxy-3,3'-dimethoxylignano-9,9'-lactone 
• 553642-31-2 2-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-benzyl]-4-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-but-3-en-1-ol 
• 774580-84-6 C₄₀H₄₀O₁₁S₃ 
• 774580-74-4 4-(bromomethyl)-2-methoxyphenyl 4-methylbenzenesulfonate 
• 773872-07-4 4-(hydroxymethyl)-2-methoxyphenyl 4-methylbenzenesulfonate 
• 774580-83-5 3-(3-methoxy-4-(tosyloxy)phenyl)-2-((tosyloxy)methyl)propanal 
• 774580-82-4 3-(3-methoxy-4-(tosyloxy)phenyl)-2-(hydroxymethyl)-1-(tosyloxy)propane 
• 774580-81-3 3-(3-methoxy-4-(tosyloxy)phenyl)-2-((tosyloxy)methyl)propyl acetate 
• 246224-09-9 4-formyl-2-methoxyphenyl-1-(4-methylbenzenesulfonate) 
• 121-33-5 vanillin 
• 69404-94-0 O-tert-butyldimethylsilylvanillin 

Relevant articles and documents

Synthesis of R-(-)-imperanene from the natural lignan hydroxymatairesinol

A convenient and high yielding method for the synthesis of R-(-)-imperanene, starting from the readily available natural lignan hydroxymatairesinol from Norway spruce, was developed. Hydroxymatairesinol was degraded in strongly basic aqueous conditions to

Enantioselective synthesis of imperanene via enzymatic asymmetrization of an intermediary 1,3-diol

(Chemical Equation Presented) Using a chemoenzymatic synthetic strategy, (S)-imperanene and its (R)-enantiomer has been synthesized from vanillin in nine steps. The key step in the synthesis involves the use of Pseudomonas cepacia lipase (PS-30) to induce

Total synthesis of (S)-(+)-imperanene. Effective use of regio- and enantioselective intramolecular carbon-hydrogen insertion reactions catalyzed by chiral dirhodium(II) carboxamidates

The total synthesis of (S)-(+)-imperanene, a natural product found in Chinese medicine, has been completed in 12 steps from a commercially available cinnamic acid. The key step is highly enantioselective carbon-hydrogen insertion from a diazoacetate using a chiral dirhodium(II) carboxamidate catalyst. An elimination process essential to the construction has been optimized to avoid intramolecular Friedel-Crafts alkylation.