163923-18-0

Basic information

• Product Name: N-(Benzyl-6-(4-phenylbutoxy)-hexane-1-aMine hydrochloride
• Synonyms: N-(Benzyl-6-(4-phenylbutoxy)-hexane-1-aMine hydrochloride;N-Benzyl-6-(4-Phenylbutoxy)Hexan-1-Amine Hydrochloride
• CAS NO: 163923-18-0
• Molecular Formula: C23H34ClNO
• Molecular Weight: 375.98
• Mol File: 163923-18-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• CAS DataBase Reference: N-(Benzyl-6-(4-phenylbutoxy)-hexane-1-aMine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(Benzyl-6-(4-phenylbutoxy)-hexane-1-aMine hydrochloride(163923-18-0)
• EPA Substance Registry System: N-(Benzyl-6-(4-phenylbutoxy)-hexane-1-aMine hydrochloride(163923-18-0)

Safety Data

• Hazardous Substances Data: 163923-18-0(Hazardous Substances Data)

Upstream product

• 3360-41-6 4-phenyl-butan-1-ol 
• 629-03-8 1 ,6-dibromohexane 
• 94749-73-2 6-bromohexyl 4-phenylbutyl ether 
• 100-46-9 benzylamine 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES

The present invention discloses a process for the preparation of methyl 2-(benzyloxy)- 5-(2-bromoacetyl)benzoate (V), comprising: (d) benzylating methyl-5-acetyl-2-hydroxybenzoate (VIII) with benzyl chloride in the presence of a base and a catalyst in a suitable polar solvent to obtain 5-acetyl-2- benzyloxy benzoate (VII); (e) brominating methyl 5-acetyl-2-(benzyloxy)benzoate (VII) with a suitable brominating agent in one or more suitable' solvents in the presence of an acid catalyst to obtain methyl 2-(benzyloxy)-5-(2-bromoacetyl)benzoate V; (c) optionally, purifying the methyl 2-(benzyloxy)-5-(2-bromoacetyl)benzoate (V) in a suitable solvent; and (f) isolating the methyl 2-(benzyloxy)-5-(2-bromoacetyl)benzoate (V).