16430-05-0

Basic information

• Product Name: Didehydro-4-methyl-5-phenyl-1,3,4-thiazolidin-2-on
• Synonyms: Didehydro-4-methyl-5-phenyl-1,3,4-thiazolidin-2-on
• CAS NO: 16430-05-0
• Molecular Weight: 192.241
• Mol File: 16430-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Didehydro-4-methyl-5-phenyl-1,3,4-thiazolidin-2-on(CAS DataBase Reference)
• NIST Chemistry Reference: Didehydro-4-methyl-5-phenyl-1,3,4-thiazolidin-2-on(16430-05-0)
• EPA Substance Registry System: Didehydro-4-methyl-5-phenyl-1,3,4-thiazolidin-2-on(16430-05-0)

Safety Data

• Hazardous Substances Data: 16430-05-0(Hazardous Substances Data)

Upstream product

• 19703-86-7 Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion 
• 75-44-5 phosgene 
• 21048-05-5 N-methylbenzothiohydrazide 

Downstream Products

• 5310-14-5 N-methylthiobenzamide 

Relevant articles and documents

Biotransformation and pharmacokinetics of mesoionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443). Studies on the biotransformation in rats

The metabolism of the antiepileptic mesoionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443) was investigated after p.o. application in rats. The main metabolite was benzoic acid, besides the unchanged material and hippuric acid the spasmodically compounds N-methyl-benzamide and mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-one were detectable. In-vitro experiments could be demonstrated that LU 2443 was not demethylated by biochemical oxidation, and LU 2443 was also very stable against metabolizing influences by enteric bacteria.