165328-45-0

Basic information

• Product Name: Benzene, 1,2,3-trifluoro-5-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-
• CAS NO: 165328-45-0
• Molecular Formula: C18H15F3O2S
• Molecular Weight: 352.377
• Mol File: 165328-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2,3-trifluoro-5-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2,3-trifluoro-5-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-(165328-45-0)
• EPA Substance Registry System: Benzene, 1,2,3-trifluoro-5-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-(165328-45-0)

Safety Data

• Hazardous Substances Data: 165328-45-0(Hazardous Substances Data)

Upstream product

• 158959-64-9 1-(2-bromocyclopenten-1-yl)-4-(methylthio)benzene 
• 75415-78-0 1,2-dibromocyclopentene 
• 158959-73-0 1-(2-bromocyclopenten-1-yl)-4-(methylsulfonyl)benzene 
• 143418-49-9 3,4,5-trifluorophenylboronic acid 
• 98546-51-1 (4-thiomethoxyphenyl)boronic acid 

Relevant articles and documents

1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

A series of 1,2-diarylcyclopentene methyl sulfones and sulfonamides have been shown to be remarkably potent and selective cyclooxygenase-2 (COX-2) inhibitors. The methyl sulfone analogs 7 showed excellent COX-2 activity, with IC50s ranging from