16618-66-9Relevant articles and documents
Discovery of DS68702229 as a potent, orally available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator
Akiu, Mayuko,Tsuji, Takashi,Iida, Kouki,Sogawa, Yoshitaka,Terayama, Koji,Yokoyama, Mika,Tanaka, Jun,Asano, Daigo,Honda, Tomohiro,Sakurai, Ken,Pinkerton, Anthony B.,Nakamura, Tsuyoshi
, p. 1110 - 1110 (2021/11/20)
Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the rate-limiting step of the nicotinamide adenine dinucleotide (NAD+) salvage pathway. Because NAD+ plays a pivotal role in energy metabolism and boosting NAD+ has
Total synthesis of the photoprotecting dipyrrolobenzoquinone (+)-terreusinone
Wang, Christy,Sperry, Jonathan
scheme or table, p. 6444 - 6447 (2012/02/05)
The first synthesis of (+)-terreusinone 1, a dipyrrolobenzoquinone with a potent UV-A protecting capability, is described. Key transformations include a one-pot Larock indolization-Sonogashira coupling reaction and the hydroamination of an unsubstituted o
RADIOLABELED FARNESYL-PROTEIN TRANSFERASE INHIBITORS
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, (2008/06/13)
The present invention is directed toward radiolabeled farnesyl-protein transferase inhibitor compounds which are useful to label FPTase in assays, whether cell-based, tissue-based or in whole animal. The tracers can also be used in competitive binding assays to obtain information on the interaction of unlabeled FTIs with FPTase.