16619-38-8Relevant articles and documents
Synthesis, molecular modeling and biological evaluation of aza-flavanones as α-glucosidase inhibitors
Kasturi, Sivaprasad,Surarapu, Sujatha,Bathoju, Chandra Chary,Uppalanchi, Srinivas,Dwivedi, Shubham,Perumal, Yogeeswari,Sigalapalli, Dilep Kumar,Babu, Bathini Nagendra,Ethiraj, Krishna S.,Anireddy, Jaya Shree
, p. 1618 - 1630 (2017/08/22)
An efficient acid catalyzed methodology has been employed to synthesize a variety of aza-flavanones and their α-glucosidase inhibitory activity is evaluated using acarbose, miglitol and voglibose as reference standards. Molecular modeling studies were per
Efficient construction of 3-arylquinolin-4(1H)-ones via in situ Meinwald rearrangement/intramolecular reductive cyclization of 2′-nitrochalcone epoxides
Wang, Sheng,Zhao, Chao,Liu, Ting,Yu, Lifang,Yang, Fan,Tang, Jie
, p. 7025 - 7031 (2016/10/14)
An efficient method for construction of 3-arylquinolin-4(1H)-ones via in situ Meinwald rearrangement/intramolecular reductive cyclization of 2′-nitrochalcone epoxides has been developed. The practical approach is of excellent functional groups compatibili
Synthesis and screening antimicrobial activities of novel 1,3-diaryl-3-(phenylthio)propan-1-one derivatives
Karaman, Isa,Gezegen, Hayreddin,Ceylan, Mustafa,Dilma, Merve
experimental part, p. 580 - 586 (2012/06/01)
In this study, a series of novel β-mercapto carbonyl derivatives (3a-j) was prepared by addition of thiophenol (2) to chalcones (1a-j) in the presence of catalytic amount of iodine (10 mol%) in CH2Cl 2. Antibacterial and antifungal in vitro properties of the synthesized compounds were tested against some human pathogenic microorganisms by employing the disk diffusion technique. For the most active compounds, also minimum inhibitory concentrations (MICs) were determined. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.