16648-51-4Relevant articles and documents
The Biodegradation of Low-molecular-weight Urethane Compounds by a Strain of Exophiala jeanselmei
Owen, Stephen,Otani, Takahito,Masaoka, Satoshi,Ohe, Tatsuhiko
, p. 244 - 248 (1996)
To further analyze the biodegradation of polyurethane polymers, we investigated the biodegradation of low-molecular-weight N-tolylcarbamate model compounds with structures closely resembling the urethane linkages found in polyurethanes based on tolylene-diisocyanate (TDT). Soil microflora were screened for microorganisms that were able to utilize toluene-2,4-dicarbamic acid, diethyl ester (compound 1) as the sole source of carbon, and the soil fungus Exophiala jeanselmei strain REN-11A was selected as the most effective strain. Several N-tolylcarbamate compounds were used, and it was found that REN-11A was able to degrade compound 1, as well as the related compound toluene-2,6-dicarbamic acid, diethyl ester, very efficiently. Further investigation showed that compound 1 was biodegraded to tolylene-2,4-diamine via the aromatic amine intermediates carbamic acid, (3-amino-4-methylphenyl)-, ethyl ester and carbamic acid, (5-amino-2-methylphenyl)-, ethyl ester.
A new access to quinazolines from simple anilines
Chilin, Adriana,Marzaro, Giovanni,Zanatta, Samuele,Barbieri, Vera,Pastorini, Giovanni,Manzini, Paolo,Guiotto, Adriano
, p. 12351 - 12356 (2007/10/03)
A new synthetic pathway to quinazolines is described. This new method uses hexamethylenetetramine in TFA and potassium ferricyanide in aqueous ethanolic KOH, starting from simple N-protected anilines. The method affords substituted quinazolines with high
