16662-46-7 Usage
Description
Methoxyverapamil hydrochloride, also known as gallopamil hydrochloride, is a potent methoxy analog of the calcium channel blocker verapamil. It exhibits a similar profile to verapamil and is used in the treatment of angina and auricular arrhythmia. It is available under various brand names, including Benpredil, Corapamil, and PROCORUM.
Uses
Used in Pharmaceutical Industry:
Methoxyverapamil hydrochloride is used as a calcium channel blocker for the treatment of angina and auricular arrhythmia. It helps to relax blood vessels and improve blood flow, providing relief from chest pain and irregular heartbeats.
Used in Cardiology:
Methoxyverapamil hydrochloride is used as an anti-anginal and anti-arrhythmic agent in cardiology. It is effective in managing symptoms of angina by reducing the workload on the heart and preventing the occurrence of auricular arrhythmias, thus improving the overall cardiovascular health of patients.
Used in Drug Development:
Methoxyverapamil hydrochloride serves as a valuable compound in drug development for the discovery of new calcium channel blockers with improved potency and selectivity. Its structure and pharmacological properties provide a basis for the design and synthesis of novel therapeutic agents targeting cardiovascular diseases.
Originator
Knoll (W. Germany)
Check Digit Verification of cas no
The CAS Registry Mumber 16662-46-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,6 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 16662-46:
(7*1)+(6*6)+(5*6)+(4*6)+(3*2)+(2*4)+(1*6)=117
117 % 10 = 7
So 16662-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H38N2O5.ClH/c1-8-27(19-28,21-17-23(31-4)26(34-7)24(18-21)32-5)14-10-15-29(2)16-13-20-11-9-12-22(30-3)25(20)33-6;/h9,11-12,17-18H,8,10,13-16H2,1-7H3;1H
16662-46-7Relevant articles and documents
Preparation of phenylacetonitriles carrying basic substituents
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, (2008/06/13)
A process for the preparation of phenylacetonitriles, carrying basic substituents, of the formula I STR1 where R1, R2, R3, R4, R5, R6, R7 and R8 have the meanings given in the description, by reacting an aldehyde of the formula II STR2 with an amine of the formula III STR3
