16707-70-3

Basic information

• Product Name: Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-
• CAS NO: 16707-70-3
• Molecular Formula: C10H11NO3S
• Molecular Weight: 225.268
• Mol File: 16707-70-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-(16707-70-3)
• EPA Substance Registry System: Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-(16707-70-3)

Safety Data

• Hazardous Substances Data: 16707-70-3(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 1197342-75-8 Z-Gly-STrt 
• 1330059-26-1 N-benzyloxycarbonylglycine 9-fluorenylmethyl thioester 
• 2899-57-2 Sphenyl N-benzyloxycarbonylaminoethanothioate 

Downstream Products

• 16707-71-4 N^α-Benzoyl-S-benzyloxycarbonylglycyl-L-cysteinamid 
• 16707-72-5 N-Benzoyl-S--(+/-)-cysteinamid 
• 238748-85-1 benzyl N-<2-<<1,1-dimethyl-2--2-thioxoethyl>amino>-2-oxoethyl>carbamate 
• 238748-87-3 benzyl N-<2-<<1,1-dimethyl-2--2-oxoethyl>amino>-2-thioxoethyl>carbamate 
• 142053-52-9 Z-Gly-L-Val-L-Val-L-Phe-OMe 
• 56414-65-4 1-(2-benzyloxycarbonylamino-1-oxo-ethyl)-pyrrolidine 
• 108849-83-8 N-(N-benzyloxycarbonyl-glycyl)-L-serine methyl ester 
• 6206-42-4 N-benzyloxycarbonylglycyl-L-phenylalanine methyl ester 
• 6833-09-6 benzyl (2-oxo-2-(phenylamino)ethyl)carbamate 
• 2642-32-2 benzyl (2-(benzylamino)-2-oxoethyl)carbamate 
• 66012-26-8 N-benzyloxycarbonylglycyl-L-tyrosine methyl ester 
• 6216-46-2 2-acetamido-1-N--2-deoxy-β-D-glycopyranosylamine 
• 6216-47-3 N-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-Nα-(benzyloxycarbonyl)glycineamide 

Relevant articles and documents

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In situ carboxyl activation using a silatropic switch: A new approach to amide and peptide constructions

The novel reactivity of O-silylthionoesters with amine nucleophiles to generate oxoamides (rather than thioamides) is described. A straightforward first-generation trimethylsilylation protocol using bistrimethylsilylacetamide (BSA) combined with the unique reactivity of the O-silylthionoesters toward 1° and 2° amines to generate oxoamides provides the simplest means of activating a thiol acid for peptide bond formation at neutral pH. Excellent stereoretention is observed.

A novel acid-catalyzed isomerization of Aib-containing thiodipeptides

The use of amino thioacids in the 'azirine/oxazolone method' led to completely epimerized Aib-containing endothiodipeptides (Aib=2- aminoisobutyric acid). It could be established that the epimerization occurred during the acidic hydrolysis of the primaril