1671-18-7

Basic information

• Product Name: 2-CHLORO-1-METHYL-(4-METHYLSULFONYL) BENZENE
• Synonyms: 2-CHLORO-1-METHYL-(4-METHYLSULFONYL) BENZENE;2-Chlor-4-(methylsulfonyl)toluol;2-Chloro-4-(methylsulfonyl)toluene;3-Chloro-4-methylphenyl methyl sulfone;2-Chloro-1-Methyl-4-(Metylsulfonyl)-benzene;2-Chloro-4-Methylsulfonyl benzene
• CAS NO: 1671-18-7
• Molecular Formula: C₈H₉ClO₂S
• Molecular Weight: 204.67
• Mol File: 1671-18-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 95-96 °C
• Boiling Point: 351°Cat760mmHg
• Flash Point: 166.1°C
• Appearance: /
• Density: 1.283g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-CHLORO-1-METHYL-(4-METHYLSULFONYL) BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-1-METHYL-(4-METHYLSULFONYL) BENZENE(1671-18-7)
• EPA Substance Registry System: 2-CHLORO-1-METHYL-(4-METHYLSULFONYL) BENZENE(1671-18-7)

Safety Data

• Hazardous Substances Data: 1671-18-7(Hazardous Substances Data)

Usage

Uses

2-Chloro-1-methyl-(4-methylsulfonyl)benzene can be used as herbicides.

InChI:InChI=1/C8H9ClO2S/c1-6-3-4-7(5-8(6)9)12(2,10)11/h3-5H,1-2H3

Upstream product

• 95-73-8 2,4-dichlorotoluene 
• 20277-69-4 sodium methansulfinate 
• 488737-19-5 4-methyl-3-chlorobenzenesulfinic acid 
• 3185-99-7 Methyl p-tolyl sulfone 
• 53250-85-4 3-Chloro-4-methylphenyl methyl sulphide 

Downstream Products

• 879085-55-9 vismodegib 
• 53250-83-2 2-chloro-4-(methanesulfonyl)benzoic acid 
• 106904-10-3 2-chloro-4-(methylsulphonyl)benzoyl chloride 
• 1671-39-2 3-Chlor-5-methylsulfonyl-2-methyl-benzol-sulfonsaeure-⁽²⁾-anilid 
• 1671-38-1 3-Chlor-5-methylsulfonyl-2-methyl-benzol-sulfonsaeure-⁽¹⁾-isopropylamid 
• 1671-37-0 3-Chlor-5-methylsulfonyl-2-methyl-benzol-sulfonsaeure-⁽¹⁾-methylamid 
• 1671-36-9 3-Chlor-5-methylsulfonyl-2-methyl-benzolsulfonamid 
• 101349-95-5 2-chloro-4-(methylsulfonyl)benzaldehyde 
• 1671-19-8 3-Chlor-5-methylsulfonyl-2-methyl-benzolsulfonylchlorid 

Relevant articles and documents

A New Class of Amide Ligands Enable Cu-Catalyzed Coupling of Sodium Methanesulfinate with (Hetero)aryl Chlorides

((2S,4R)-4-Hydroxy-N-(2-methylnaphthalen-1-yl)pyrrolidine-2-carboxamide (HMNPC), an amide derived from 4-hydroxy-L-proline and 2-methyl naphthalen-1-amine, is a powerful ligand for Cu-catalyzed coupling of (hetero)aryl halides with sulfinic acid salts, allowing for first time the metal-catalyzed coupling of (hetero)aryl chlorides and NaSO2Me. A considerable number of (hetero)aryl chlorides worked well, providing the pharmaceutically important (hetero)aryl methylsulfones in good to excellent yields.

Process for the preparation of 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and similar compounds

Process for the preparation of 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and like compounds. A process for the preparation of 4-alkyl(C1-C4)-sulfonyl-1-alkyl-2-chlorobenzenes, in very good yields and with high selectivity by selective

A Simple Synthesis of Alkoxyaryl Alkyl Sulphides from Dichlorobenzene Derivatives

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