16764-17-3

Basic information

• Product Name: 2-(4-chloro-2-nitrophenyl)ethan-1-ol
• Synonyms: 2-(4-chloro-2-nitrophenyl)ethan-1-ol
• CAS NO: 16764-17-3
• Molecular Weight: 201.609
• Mol File: 16764-17-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 311.4±27.0 °C(Predicted)
• Density: 1.404±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(4-chloro-2-nitrophenyl)ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-2-nitrophenyl)ethan-1-ol(16764-17-3)
• EPA Substance Registry System: 2-(4-chloro-2-nitrophenyl)ethan-1-ol(16764-17-3)

Safety Data

• Hazardous Substances Data: 16764-17-3(Hazardous Substances Data)

Usage

General Description

2-(4-chloro-2-nitrophenyl)ethan-1-ol is a chemical compound with the molecular formula C8H8ClNO3. It is a white to yellow crystalline solid that is used in the synthesis of various pharmaceuticals and agrochemicals. 2-(4-chloro-2-nitrophenyl)ethan-1-ol is a highly reactive intermediate in organic chemistry and is primarily used as a building block in the production of other chemicals. It is important to handle this compound with care, as it may pose a health hazard if not used properly. Additionally, it is important to consider the environmental impact of this chemical and take appropriate measures to minimize its release into the environment.

Upstream product

• 89-59-8 4-chloro-2-nitrotoluene 
• 100-85-6 N-benzyl-trimethylammonium hydroxide 
• 50-00-0 formaldehyd 

Downstream Products

• 199122-95-7 2-(4-chloro-2-nitrophenyl)ethylsulfonyl chloride 
• 807639-73-2 1-butanol,4-[2-(4-chloro-2-nitrophenyl)ethoxy]-, acetate(ester) 
• 69111-49-5 2-nitro-4-chlorophenylacetaldehyde 
• 179691-26-0 2-(4-chloro-2-nitrophenyl)ethoxycarbonyl chloride 
• 52536-97-7 4-chloro-1-(2-chloroethyl)-2-nitro-benzene 
• 620964-75-2 1-(2-bromo-ethyl)-4-chloro-2-nitro-benzene 
• 1056010-61-7 methanesulfonic acid, trifluoro-, 2-(4-chloro-2-nitrophenyl)ethyl ester 

Relevant articles and documents

Synthesis of Fused Indoline-Cyclobutanone Derivatives via an Intramolecular [2+2] Cycloaddition

A serendipitously-discovered process for the synthesis of heterocyclic products containing a novel fused indoline-cyclobutanone ring system is reported. This process is believed to take place through in situ generation of a ketene intermediate, followed b

Synthesis of indolines via a SmI2 promoted domino nitro reduction-intramolecular aza-Michael reaction

A simple and straightforward synthesis of substituted indolines based on a domino nitro reduction intramolecular aza-Michael reaction is described. The reaction employs Samarium diiodide under mild conditions for the addition of dibromoacetic acid to substituted 2-(2-nitrophenyl) acetaldehyde derivatives and their subsequent cyclization upon nitro group reduction to provide corresponding indoline heterocycles in good yields. This "one pot" strategy also permitted the expeditious synthesis of a 1,2,3,4-tetrahydroquinoline, whereas the seven-membered 2,3,4,5-tetrahydrobenzoazepines compounds were not formed under these reaction conditions.

Nucleoside derivatives with photolabile protective groups

The invention relates to nucleoside derivatives having photolabile protective groups of the general formula (I) STR1 in which R1 =H, NO2, CN, OCH3, halogen or alkyl or alkoxyalkyl having 1 to 4 C atoms R2 =H, OCH3 R3 =H, F, Cl, Br, NO2 R4 =H, halogen, OCH3, or an alkyl radical having 1 to 4 C atoms R5 =H or a usual functional group for preparing oligonucleotides R6 =H, OH, halogen or XR8, where X=O or S and R8 represents a protective group usual in nucleotide chemistry, B=adenine, cytosine, guanine, thymine, uracil, 2,6-diaminopurin-9-yl, hypoxanthin-9-yl, 5-methylcytosin-1-yl, 5-amino-4-imidazolcarboxamid-1-yl, or 5-amino-4-imidazolcarboxamid-3-yl, where in the case of B=adenine, cytosine or guanine, the primary amino function optionally exhibits a permanent protective group. These derivatives may be used for the light-controlled synthesis of oligonucleotides on a DNA chip.