16825-16-4

Basic information

• Product Name: 2-Pentadecanone,6,10,14-trimethyl-, (6R,10R)-
• Synonyms: 2-Pentadecanone,6,10,14-trimethyl-, [R-(R*,R*)]-; (+)-Phytone; (6R,10R)-6,10,14-Trimethylpentadecan-2-one; (R,R)-Phytone; Phytol ketone; Phytone; Phytone (ketone)
• CAS NO: 16825-16-4
• Molecular Formula: C₁₈H₃₆O
• Molecular Weight: 268.4778
• Mol File: 16825-16-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 316.8°Cat760mmHg
• Flash Point: 95°C
• Density: 0.828g/cm³
• CAS DataBase Reference: 2-Pentadecanone,6,10,14-trimethyl-, (6R,10R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentadecanone,6,10,14-trimethyl-, (6R,10R)-(16825-16-4)
• EPA Substance Registry System: 2-Pentadecanone,6,10,14-trimethyl-, (6R,10R)-(16825-16-4)

Safety Data

• Hazardous Substances Data: 16825-16-4(Hazardous Substances Data)

Upstream product

• 3689-69-8 (R)-6,10,14-trimethylpentadec-5-en-2-one 
• 1190-55-2 (3Ξ,7R)-3,7,11-trimethyl-dodecanoic acid 
• 123-76-2 levulinic acid 
• 59965-20-7 (R)-1-bromo-3,7-dimethyloctane 
• 1117-61-9 (3R)-citronellol 
• 85253-85-6 D-4,8-dimethyl-nonanenitrile 
• 13955-70-9 (R)-(-)-4,8-dimethylnonanoic dcid 
• 1117-60-8 (R)-3,7-dimethyloctan-1-ol 
• 141-97-9 ethyl acetoacetate 
• 6750-34-1 (3R)-3,7,11-trimethyldodecan-1-ol 
• 1117-52-8 6,10,14-trimethyl-5,9,13-pentadecatriene-2-on 
• 64611-89-8 6,10,14-trimethyl-5,9-pentadecadien-2-one 
• 1616077-92-9 C₂₀H₄₀O₂ 
• 1616077-91-8 2-methyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7-dien-1-yl)-1,3-dioxolane 

Downstream Products

• 5492-30-8 (Z)-phytol 
• 150-86-7 phytol 
• 6750-34-1 (3R,7R)-hexahydrofarnesol 
• 18920-63-3 vitamin E 
• 14745-36-9 2-((7R,11R)-3-Hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethylbenzene-1,4-diol 
• 7559-04-8 2-[(3R,7R,11R)-3-hydroxy-3,7,11,15-tetramethylhexadecyl]-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione 
• 91418-95-0 (3R,7R,11R)-1-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-3,7,11,15-tetramethyl-hexadecan-3-ol 
• 32466-45-8 (2R,4'R,8'R)-α-tocopheryl methyl ether 
• 1290041-53-0 (2RS,6R,10R)-6,10,14-trimethylpentadec-2-yl-2-(N-benzyloxycarbonyl)-L-valinate 
• 118100-85-9 trans-(RR/SS)-phytol 
• 118100-92-8 cis-(RR/SS)-phytol 
• 10339-74-9 (4R,8R)-4,8,12-trimethyl-tridecanoic acid methyl ester 
• 59-02-9 Tocopherol 
• 119-98-2 (2RS,4'R,8'R)-Tocol 

Relevant articles and documents

Discrimination of stereoisomers by one-dimensional 13C NMR: All 16 stereoisomers of 4-hydroxy-α-tocopherol resolved

-

(6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10,14-TRIMETYLPENTADECA-5,9,13-TRIEN-2-ONE OR 6,10,14-TRIMETYLPENTADECA-5,9-DIEN-2-ONE

The present invention relates to a process of manufacturing (6R,10R)- 6,10,14-trimetylpentadecan-2-one in a multistep synthesis from a mixture of (5E,9E)-, (5E,9Z)-, (5Z,9E)- and (5Z.9Z)- isomers of 6, 10, 14-trimetylpentadeca- 5,9,13-trien-2-one or 6,10,14-trimetylpentadeca-5,9-dien-2-one. The process is very advantageous in that it forms in an efficient way the desired chiral product from a mixture of stereoisomers of the starting product.

PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS

The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.