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168266-51-1

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  • 3-PIPERIDINAMINE,N-[[2-METHOXY-5-[5-(TRIFLUORO-METHYL)-1H-TETRAZOL-1-YL]PHENYL]METHYL]-2-PHENYL-,2HCL,(2S,3S)-3-PIPERIDINAMINE,N-[[2-METHOXY-5-[5-(TRIFLUOROMETHYL)-1H-TETRAZOL-1-YL]PHENYL]METHYL]-2-PH

    Cas No: 168266-51-1

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168266-51-1 Usage

Chemical Properties

Yellowish solid

Uses

Antiemetic (tachykinin NK1receptor antagonist).

Check Digit Verification of cas no

The CAS Registry Mumber 168266-51-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,2,6 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 168266-51:
(8*1)+(7*6)+(6*8)+(5*2)+(4*6)+(3*6)+(2*5)+(1*1)=161
161 % 10 = 1
So 168266-51-1 is a valid CAS Registry Number.
InChI:InChI=1/C21H23F3N6O.2ClH/c1-31-18-10-9-16(30-20(21(22,23)24)27-28-29-30)12-15(18)13-26-17-8-5-11-25-19(17)14-6-3-2-4-7-14;;/h2-4,6-7,9-10,12,17,19,25-26H,5,8,11,13H2,1H3;2*1H

168266-51-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3S)-N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-2-phenylpiperidin-3-amine,dihydrochloride

1.2 Other means of identification

Product number -
Other names Vofopitant dihydrochloride (USAN)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:168266-51-1 SDS

168266-51-1Upstream product

168266-51-1Downstream Products

168266-51-1Relevant articles and documents

Piperidine derivatives

-

, (2008/06/13)

The present invention relates to piperidine derivatives of formula (I) STR1 wherein R 1 is a C 1-4 alkoxy group; R 2 is STR2 R 3 is a hydrogen or halogen atom; R 4 and R 5 may each independently represent a hydrogen or halogen atom, or aC 1-4 alkyl, C 1-4 alkoxy or trifluoromethyl group;R 6 is a hydrogen atom, a C 1-4 alkyl, (CH 2) m cyclopropyl, --S(O) n C 1-4 alkyl, phenyl,NR 7 R 8, CH 2 C(O)CF 3 or trifluoromethyl group;R 7 and R 8 may each independently represent a hydrogen atom, or a C 1-4 alkyl or acyl group;x represents zero or 1;n represents zero, 1 or 2;m represents zero or 1;and pharmaceutically acceptable salts and solvates thereof; to processes for their preparation; and their use in the treatment of conditions mediated by tachykinins.

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