168296-33-1

Basic information

• Product Name: OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN
• Synonyms: Octakis-6-iodo-6-deoxy-γ-cyclodextrin;octakis(6-deoxy-6-iodo)-gamma-cyclodextrin;octakis(6-deoxy-6-iodo)-γ-cyclodextrin;6-deoxy-6-iodo-gamma-cyclodextrin;γ-Cyclodextrin,6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy-6A,6B,6C,6D,6E,6F,6G,6H-octaiodo
• CAS NO: 168296-33-1
• Molecular Formula: C₄₈H₇₂I₈O₃₂
• Molecular Weight: 2176.30184
• EINECS: 1312995-182-4
• Mol File: 168296-33-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: 208-212°C
• Appearance: Off-white/Solid powder
• Density: 2.245±0.06 g/cm3(Predicted)
• Solubility: Soluble in DMF, DMSO. Insoluble in water, methanol, chloroform.
• PKA: 11.60±0.70(Predicted)
• CAS DataBase Reference: OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN(CAS DataBase Reference)
• NIST Chemistry Reference: OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN(168296-33-1)
• EPA Substance Registry System: OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN(168296-33-1)

Safety Data

• Hazardous Substances Data: 168296-33-1(Hazardous Substances Data)

Usage

Chemical Properties

off-white powder

Uses

6A,6B,6C,6D,6E,6F,6G,6H-Octadeoxy-6A,6B,6C,6D,6E,6F,6G,6H-octaiodo-γ-cyclodextrin is a useful chemical compound for preparation of isothiocyanates and cyclic thiocarbamates of trehalose sucrose and cyclomaltooligosaccharides.

Upstream product

• 17465-86-0 cyclomaltooctaose 

Downstream Products

• 156297-61-9 6^A,6^B,6^C,6^D,6^E,6^F,6^G,6^H-octaazido-6^A,6^B,6^C,6^D,6^E,6^F,6^G,6^H-octadeoxy-γ-cyclodextrin 

Relevant articles and documents

Solubilization of polycyclic aromatics in water by γ-cyclodextrin derivatives

A series of hydrophilic per-6-thio-6-deoxy-γ-cyclodextrins (CDs) were synthesized from per-6-iodo-6-deoxy-γ-CD. These new hosts are able to solubilize polycyclic aromatic guests in aqueous solution to much higher extents than native CDs. Phase-solubility diagrams were mostly linear in accordance with both 1:1 and 1:2 CD-guest complexes in aqueous solution. The stoichiometry of the inclusion complexes was further investigated by fluorescence spectroscopy, which revealed very pronounced Stokes shifts typical for 1:2 complexes. This finding was further consolidated by quantum mechanical calculations of dimer formation of the guests and space-filling considerations by using the cross-sectional areas of the CDs and guests. The calculated dimerization energies correlated well with the binding free energies measured for the 1:2 complexes, and provided the main contribution to the driving force of complexation in the γ-CD cavity. Copyright

Method for synthesizing beta-hydroxy carbonyl compound by catalyzing asymmetric Aldol reaction in water phase

The invention discloses a method for synthesizing a beta-hydroxy carbonyl compound by catalyzing asymmetric Aldol reaction in a water phase. The method comprises the following steps: in the water phase, catalyzing ketone and aldehyde with equal molar weig

β-Cyclodextrin Covalent Organic Framework for Selective Molecular Adsorption

Covalent organic frameworks (COF) are complex functional systems constructed with atomic precision by linking well-defined building blocks through robust covalent bonds. β-cyclodextrin (β-CD) is a most employed supramolecule which bears a hydrophobic cavity guiding molecular specific recognitions. Building COF with asymmetric β-CD linkers is challenging and has never been reported. Here, β-CD COF is grown with heptakis(6-amino-6-deoxy)-β-CD and terephthalaldehyde in green solvents of water and ethanol at room temperature. The COF is characterized by powder X-ray diffraction, which matches well with the simulated crystal structure. Weaving β-CD into a framework through reticular chemistry allows the integration of a large amount of β-CD units (50 mol %), much higher than β-CD polymers. The β-CD COF has larger surface area, more uniform pore size, and higher thermal stability than the non-crystalline β-CD polymer produced by the same reagents. Finally, the β-CD COF holds abundant specific interaction sites enabling selective molecular adsorption.