16861-22-6

Basic information

• Product Name: 2,3-Dichloro-4-hydroxybenzaldehyde
• Synonyms: 2,3-DICHLORO-4-HYDROXYBENZALDEHYDE;2,3-Dichloro-4-hydroxybenzaldehyde 97%;2,3-Dichloro-4-formylphenol;Benzaldehyde,2,3-dichloro-4-hydroxy-;2,3-Dichloro-4-hydroxybenzaldehyde97%
• CAS NO: 16861-22-6
• Molecular Formula: C₇H₄Cl₂O₂
• Molecular Weight: 191.01
• Product Categories: Aldehydes;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 16861-22-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 184-185 °C
• Boiling Point: 278.629 °C at 760 mmHg
• Flash Point: 122.311 °C
• Appearance: /
• Density: 1.548 g/cm³
• Vapor Pressure: 0.00249mmHg at 25°C
• Refractive Index: 1.643
• PKA: 5.36±0.23(Predicted)
• CAS DataBase Reference: 2,3-Dichloro-4-hydroxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dichloro-4-hydroxybenzaldehyde(16861-22-6)
• EPA Substance Registry System: 2,3-Dichloro-4-hydroxybenzaldehyde(16861-22-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 16861-22-6(Hazardous Substances Data)

Usage

General Description

2,3-Dichloro-4-hydroxybenzaldehyde is a compound with the molecular formula C7H4Cl2O2. It is a yellow solid that is soluble in organic solvents like ether and chloroform. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. Its structure consists of a benzene ring with two chlorine atoms and a hydroxyl group attached, as well as an aldehyde functional group. 2,3-Dichloro-4-hydroxybenzaldehyde is known for its strong odor and is considered to be a potentially hazardous chemical if not handled and stored properly.

InChI:InChI=1/C7H4Cl2O2/c8-6-4(3-10)1-2-5(11)7(6)9/h1-3,11H

Upstream product

• 1984-59-4 2,3-dichloroanisole 
• 41827-86-5 2,3-dichloro-4-methoxy-benzaldehyde 
• 67-66-3 chloroform 
• 576-24-9 2,3-dichlorophenol 

Downstream Products

• 387873-65-6 2,3-dichloro-4-(2-isopropyl-phenylsulfanyl)-benzaldehyde 
• 133495-72-4 (Z)-3-(4-Allyloxy-2,3-dichloro-phenyl)-2-azido-acrylic acid ethyl ester 
• 133495-79-1 C₃₂H₂₈Cl₂NO₃P 
• 16861-23-7 ethyl <2,3-dichloro-4-formylphenoxy> acetate 

Relevant articles and documents

DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE

The present invention relates to compounds derived from substituted 3-phenyl-1-(thien-2-yl)propan-1-ones, pharmaceutical compositions comprising them as well as their therapeutic applications, notably in the field of human and animal health.

HYDROXY-BIPHENYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS

This invention provides estrogen receptor modulators having the structure formula (I): wherein R1 to R6 and R8 are as defined in the specification; or a pharmaceutically acceptable salt thereof.

Synthesis and Spectroscopic Data of Chlorinated 4-Hydroxybenzaldehydes

All chlorinated 4-hydroxybenzaldehydes including three hitherto unknown compounds have been synthesized from chlorinated phenols by applying the Reimer-Tiemann method. (1)H NMR, (13)C NMR, and mass-spectral data on all compounds are reported.