16865-06-8 Usage
General Description
4,7-dibromo-2-chloro-1H-benzo[d]imidazole is a chemical compound with a molecular formula C7H3Br2ClN2. It is a benzimidazole derivative with two bromine atoms and one chlorine atom attached to the benzene ring, along with two nitrogen atoms. 4,7-dibromo-2-chloro-1H-benzo[d]imidazole is used in organic synthesis as a starting material for the production of various pharmaceuticals and agrochemicals. It has also been studied for its potential use as an antifungal and antibacterial agent. Additionally, it has been investigated for its potential as a corrosion inhibitor and in the development of new materials. However, its specific applications and properties are still undergoing further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 16865-06-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,6 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 16865-06:
(7*1)+(6*6)+(5*8)+(4*6)+(3*5)+(2*0)+(1*6)=128
128 % 10 = 8
So 16865-06-8 is a valid CAS Registry Number.
16865-06-8Relevant articles and documents
Divergent Synthesis of Chiral Covalent Organic Frameworks
Wang, Li-Ke,Zhou, Jing-Jing,Lan, Yu-Bao,Ding, San-Yuan,Yu, Wei,Wang, Wei
, p. 9443 - 9447 (2019)
Featuring the simultaneous generation of a library of compounds from a certain intermediate, divergent synthesis has found increasing applications in the construction of natural products and potential medicines. Inspired by this approach, presented herein is a general strategy to introduce functionality, in a divergent manner, into covalent organic frameworks (COFs). This modular protocol includes two stages of covalent assembly, through which functional COFs can be constructed by a three-step transformation of a key platform molecule, such as 4,7-dibromo-2-chloro-1H-benzo[d]imidazole (DBCBI). Constructed herein are four types of chiral COFs (CCOFs) from DBCBI by nucleophilic substitution, Suzuki coupling, and imine formation. The unique array of eight isoframework CCOFs allowed investigation of their catalytic performance and structure–activity relationship in an asymmetric amination reaction.
