168975-75-5 Usage
Description
2-chloro-4-cyclopropylpyridine is a halogenated pyridine chemical compound with the molecular formula C8H7ClN. It features a cyclopropyl group attached to the pyridine ring, which contributes to its unique chemical and physical properties. 2-chloro-4-cyclopropylpyridine is known for its versatility in chemical reactions and its utility as a building block in the synthesis of various organic compounds, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2-chloro-4-cyclopropylpyridine is used as a key intermediate in the synthesis of pharmaceutical drugs. Its cyclopropyl functionality allows for the modification of organic molecules, enhancing the drug's efficacy and selectivity. The halogenation of the compound adds further versatility, enabling it to participate in a wide range of chemical reactions, which is crucial for the development of new and improved medications.
Used in Organic Synthesis:
In the field of organic synthesis, 2-chloro-4-cyclopropylpyridine serves as a valuable building block for the creation of complex organic molecules. Its unique structure and reactivity make it an ideal candidate for the synthesis of various compounds, including those with potential applications in materials science, agrochemicals, and other specialized industries.
Used in Drug Development:
2-chloro-4-cyclopropylpyridine is employed as a reagent in drug development processes. Its chemical and physical properties make it a useful component in the production of pharmaceuticals, contributing to the overall effectiveness and safety of the final drug product. By incorporating this compound into the synthesis of new drugs, researchers can explore novel therapeutic approaches and improve the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 168975-75-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,9,7 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 168975-75:
(8*1)+(7*6)+(6*8)+(5*9)+(4*7)+(3*5)+(2*7)+(1*5)=205
205 % 10 = 5
So 168975-75-5 is a valid CAS Registry Number.
168975-75-5Relevant articles and documents
ASK1 INHIBITING AGENTS
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Page/Page column 72, (2018/09/08)
Provided are compounds of Formulas (I'), (I), (II') and (II), or pharmaceutically acceptable salts thereof, and methods for their use and production.
Chemoselective sp 2-sp3 cross-couplings: Iron-catalyzed alkyl transfer to dihaloaromatics
Malhotra, Sushant,Seng, Pamela S.,Koenig, Stefan G.,Deese, Alan J.,Ford, Kevin A.
supporting information, p. 3698 - 3701 (2013/08/23)
The chemoselective functionalization of a range of dihaloaromatics with methyl, cyclopropyl, and higher alkyl Grignard reagents via iron-catalyzed cross-coupling is described. The site selectivity of C-X (X = halogen) activation is determined by factors such as the position of the halogen on the ring, the solvent, and the nucleophile. A one-pot protocol for the chemoselective synthesis of mixed dialkyl heterocycles is achieved solely employing iron catalysis.
