170450-78-9

Basic information

• Product Name: 2(R)-Isobutyl-3(S)-methylsuccinic acid 1-<4(S)-(phenylmethyl)-2-oxooxazolidinamide>-4-(tert-butyl ester)
• Synonyms: 2(R)-Isobutyl-3(S)-methylsuccinic acid 1-<4(S)-(phenylmethyl)-2-oxooxazolidinamide>-4-(tert-butyl ester)
• CAS NO: 170450-78-9
• Molecular Weight: 403.519
• Mol File: 170450-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(R)-Isobutyl-3(S)-methylsuccinic acid 1-<4(S)-(phenylmethyl)-2-oxooxazolidinamide>-4-(tert-butyl ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(R)-Isobutyl-3(S)-methylsuccinic acid 1-<4(S)-(phenylmethyl)-2-oxooxazolidinamide>-4-(tert-butyl ester)(170450-78-9)
• EPA Substance Registry System: 2(R)-Isobutyl-3(S)-methylsuccinic acid 1-<4(S)-(phenylmethyl)-2-oxooxazolidinamide>-4-(tert-butyl ester)(170450-78-9)

Safety Data

• Hazardous Substances Data: 170450-78-9(Hazardous Substances Data)

Upstream product

• 113543-30-9 (S)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one 
• 111757-80-3 (-)-(2S)-trifluoromethanesulfonyloxy-propionic acid tert-butyl ester 
• 13650-70-9 (+)-tert-butyl D-lactate 

Downstream Products

• 168158-38-1 (2R,3S)-N⁴-Benzyloxy-2-isobutyl-3-methyl-N¹-((S)-methylcarbamoyl-phenyl-methyl)-succinamide 
• 168158-16-5 KB-R₇₇₈₅ 
• 168393-56-4 (2S,3R)-2,5-Dimethyl-3-[((S)-methylcarbamoyl-phenyl-methyl)-carbamoyl]-hexanoic acid 
• 188728-99-6 (2S,3R)-2,5-Dimethyl-3-[((S)-methylcarbamoyl-phenyl-methyl)-carbamoyl]-hexanoic acid tert-butyl ester 

Relevant articles and documents

Asymmetric Synthesis of 2,3-Disubstituted Succinates via Chiral Oxazolidinone Controlled Displacement of α-Trifluoromethanesulfonate Substituted Esters

The addition of chiral imides to α-trifluoromethanesulfonate esters gave chiral 2,3-disubstituted succinates with moderate to excellent diastereoselectivity and in good overall chemical yields.Both syn and anti chiral products are attainable via this methodology, with generally better diastereoselectivity and chemical yields observed in the production of the syn products.The reactions proceed through the predicted SN2 displacement of the triflate leaving group, as inferred from the absolute configuration of the products.