170802-47-8

Basic information

• Product Name: Acetamide, N-2-benzothiazolyl-2-cyano- (9CI)
• Synonyms: Acetamide, N-2-benzothiazolyl-2-cyano- (9CI)
• CAS NO: 170802-47-8
• Molecular Formula: C₁₀H₇N₃OS
• Molecular Weight: 217.24708
• Product Categories: BENZOTHIAZOLE
• Mol File: 170802-47-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetamide, N-2-benzothiazolyl-2-cyano- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-2-benzothiazolyl-2-cyano- (9CI)(170802-47-8)
• EPA Substance Registry System: Acetamide, N-2-benzothiazolyl-2-cyano- (9CI)(170802-47-8)

Safety Data

• Hazardous Substances Data: 170802-47-8(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 36140-83-7 1-cyanoacetyl-3,5-dimethylpyrazole 
• 64992-14-9 acetic 2-cyanoacetic anhydride 
• 105-56-6 ethyl 2-cyanoacetate 
• 372-09-8 cyanoacetic acid 

Downstream Products

• 170802-57-0 (E)-N-Benzothiazol-2-yl-2-cyano-3-(4-methoxy-phenyl)-acrylamide 
• 1128027-14-4 C₂₅H₁₆ClN₃O₂S 
• 1128027-12-2 C₂₆H₁₉N₃O₃S 
• 1128027-02-0 C₁₇H₁₃N₅OS 
• 1128026-98-1 C₁₆H₁₀ClN₅OS 
• 1128027-00-8 C₁₆H₁₀BrN₅OS 

Relevant articles and documents

Synthesis, characterization, and biological activities of 4-imino-3-arylazo-4H-pyrimido[2,1-b][1,3]benzothiazole-2-oles

4-Imino-3,4-dihydro-2H-pyrimido[2,1-b][1,3] benzothiazole-2-one (3) was synthesized by the reaction of 2-aminobenzothiazole with ethyl cyanoacetate in solvent free conditions at 150°C. A series of pyrimido benzothiazole-based azo dyes 4( a-m) were obtained by the coupling of carbocyclic amine-based diazonium chloride with compound (3). The synthesized dyes were purified and characterized by elemental analysis, FT-IR, 1 H NMR, and high-resolution mass spectral data. The solvatochromic behaviors of dyes in various solvents were examined. All the azo dyes exhibited pronounced in vitro antibacterial activities against Gram-positive and Gram-negative bacteria, as well as fungi. The results revealed that most of the compounds exhibited good levels of antibacterial activity. Compounds 4d and 4h showed excellent levels of antimicrobial activity with MIC values of 8.25 μg/mL. Springer Science+Business Media 2014.

Synthesis of some novel benzothiazole derivatives

Novel 1,2,4-triazine, pyridine, and benzopyran derivatives have been synthesized from N-(2-benzothiazolyl)cyanoacetamide via its reaction with some electrophiles. The structure of the synthesized compounds was established by analytical and spectral data. Copyright Taylor & Francis Group, LLC.

SYNTHESIS AND PROPERTIES OF SUBSTITUTED 1-(2-BENZOTHIAZOLYL)-2-PYRIDONES

The studied 1-(2-benzothiazolyl)-2-pyridones Va-Vf were prepared from N-(2-benzothiazolyl)cyanoacetamide (II) which on reaction with 4-substituted benzaldehydes afforded 3-aryl-N-(2-benzothiazolyl)-2-cyano-2-propenamides IVa-IVg.Compounds IVa-IVf were cyclized with malonodinitrile in the presence of piperidine to give the corresponding pyridones Va-Vf.