170847-18-4
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Basic information
- Product Name: (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
- Synonyms: (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID;(RS)-APICA
- CAS NO:170847-18-4
- Molecular Formula: C10H12NO5P
- Molecular Weight: 257.18
- EINECS: N/A
- Product Categories: Glutamate receptor
- Mol File: 170847-18-4.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Desiccate at +4°C
- Solubility: N/A
- CAS DataBase Reference: (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID(CAS DataBase Reference)
- NIST Chemistry Reference: (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID(170847-18-4)
- EPA Substance Registry System: (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID(170847-18-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 170847-18-4(Hazardous Substances Data)
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170847-18-4 Usage
Uses
(RS)-APICA is a group II metabotropic glutamate receptor antagonist.Biological Activity
The rigidified analog of MPPG ((RS)-a-Methyl-4-phosphonophenylglycine ); a selective group II metabotropic glutamate receptor antagonist (IC 50 = 30 μ M) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses an unusual inverse agonist-like action.Check Digit Verification of cas no
The CAS Registry Mumber 170847-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,8,4 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.Calculate Digit Verification of CAS Registry Number 170847-18:
(8*1)+(7*7)+(6*0)+(5*8)+(4*4)+(3*7)+(2*1)+(1*8)=144
144 % 10 = 4
So 170847-18-4 is a valid CAS Registry Number.
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(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
