170917-07-4Relevant articles and documents
Synthesis of enantiopure α'-amino α,β-epoxy ketones from α'-amino bromomethyl ketones
Barluenga, Jose,Baragana, Beatriz,Concellon, Jose M.,Pinera-Nicolas, Alejandro,Rosario Diaz,Garcia-Granda, Santiago
, p. 5048 - 5052 (1999)
Preparation of enantiomerically pure α'-amino α,β-epoxy ketones 2 in an efficient synthesis starting from α'-amino bromomethyl ketones 5 and the obtention of amino diepoxido 10a as synthetic application of 2 are described. We also report the generalization of the synthesis of 1-aminoalkyl halomethyl ketones to their bromo derivatives.
