172297-36-8

Basic information

• Product Name: (Naphthyl-⁽²⁾)-(2-hydroxy-naphthyl-⁽¹⁾)-aether
• Synonyms: (Naphthyl-⁽²⁾)-(2-hydroxy-naphthyl-⁽¹⁾)-aether
• CAS NO: 172297-36-8
• Molecular Weight: 286.33
• Mol File: 172297-36-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Naphthyl-⁽²⁾)-(2-hydroxy-naphthyl-⁽¹⁾)-aether(CAS DataBase Reference)
• NIST Chemistry Reference: (Naphthyl-⁽²⁾)-(2-hydroxy-naphthyl-⁽¹⁾)-aether(172297-36-8)
• EPA Substance Registry System: (Naphthyl-⁽²⁾)-(2-hydroxy-naphthyl-⁽¹⁾)-aether(172297-36-8)

Safety Data

• Hazardous Substances Data: 172297-36-8(Hazardous Substances Data)

Upstream product

• 573-97-7 1-bromo-2-naphthol 
• 135-19-3 β-naphthol 
• 56-23-5 tetrachloromethane 
• 79718-59-5 1,1'-sulfonylbis(naphthalen-2-ol) 
• 7732-18-5 water 
• 773-90-0 1-diazo-2(1H)naphthalenone 

Downstream Products

• 135-19-3 β-naphthol 

Relevant articles and documents

Synthesis of structurally diversified BINOLs and NOBINs via palladium-catalyzed C-H arylation with diazoquinones

Privileged biaryl frameworks, BINOL and NOBIN, were efficiently constructed with sole 1-DNQs as arylation reagents under one set of reaction conditions. The judicious selection of palladium-catalytic system plays a pivotal role in the excellent selectivities. This transformation accommodated fairly broad substrate generality for both 2-naphthol and N-Boc-2-naphthylamine and afforded the structurally diversified BINOLs and NOBIN derivatives in high efficiency. Notably, the bromo-substituents which cannot survive in conventional palladium-catalyzed reactions were well-compatible with this set of conditions, providing an effective handle for further enriching the library of BINOLs and NOBINs. Preliminary attempts on the asymmetric variant of this reaction were also performed with up to 80:20 er for BINOLs synthesis. [Figure not available: see fulltext.].