17242-86-3

Basic information

• Product Name: 5-fluoro-1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione
• Synonyms: 5-fluoro-1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione
• CAS NO: 17242-86-3
• Molecular Weight: 574.519
• Mol File: 17242-86-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-fluoro-1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione(17242-86-3)
• EPA Substance Registry System: 5-fluoro-1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione(17242-86-3)

Safety Data

• Hazardous Substances Data: 17242-86-3(Hazardous Substances Data)

Upstream product

• 4348-69-0 C₃₀H₂₄N₂O₉ 
• 3083-77-0 araU 
• 613-90-1 benzoyl cyanide 

Downstream Products

• 131-06-6 1-(β-D-arabinofuranosyl)-5-fluorouracil 
• 131-06-6 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-4-hydroxy-1H-pyrimidin-2-one 
• 4298-10-6 5-fluoro-1-(β-D-arabinofuranosyl)cytosine 

Relevant articles and documents

Synthesis of O2,2′-cyclo-β-D-arabinofuranosyl- and β-D-arabinofuranosyl-5-fluorocytosine

Methods for the synthesis of 5-fluorocytosine by direct fluorination of cytidine tetraacetate with elementary fluorine in acetic acid and by amination of 5-fluorouridine triacetate by the action of sodium hydride and p-toluenesulfonyl chloride and subsequent ammonolysis were studied. 5-Fluorocytidine was converted to O2, 2′-cyclo-β-D-arabinofuranosyl-5-fluorocytosine by the successive action of acetylsalicylyl chloride and acetyl chloride in methanol to remove the protective groups. Removal of the protective groups by means of a methanol solution of ammonia gave β-D-arabinofuranosyl-5-fluorocytosine. The latter was also obtained by amination of β-D-arabinofuranosyl-5-fluorouracil tribenzoate.