172585-57-8

Basic information

• Product Name: (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester
• Synonyms: (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester
• CAS NO: 172585-57-8
• Molecular Weight: 182.195
• Mol File: 172585-57-8.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester(172585-57-8)
• EPA Substance Registry System: (R)-acetic acid 1-(4-fluoro-phenyl)-ethyl ester(172585-57-8)

Safety Data

• Hazardous Substances Data: 172585-57-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 403-41-8 (R)-1-(4-fluorophenyl)ethan-1-ol 
• 108-05-4 vinyl acetate 
• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 141-78-6 ethyl acetate 
• 876-27-7 4-chlorophenyl acetate 
• 108-22-5 Isopropenyl acetate 
• 147164-48-5 1-(4-fluorophenyl)ethenyl acetate 
• 108-58-7 Resorcinol diacetate 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 403-41-8 (R)-1-(4-fluorophenyl)ethan-1-ol 

Relevant articles and documents

Optically active 2-amino-4-alkoxypyrimidnes derivatives as 5-HT2C agonists

The present invention provides an optically active 2-amino-4-alkoxy pyrimidine derivative that has excellent performance as a 5-HT2C agonist but has high selectivity to 2A and 2B. The present invention provides the optically active 2-amino-4-alkoxy pyrimidine derivative having a structure of chemical formula 1.COPYRIGHT KIPO 2020

Base-Free Dynamic Kinetic Resolution of Secondary Alcohols with a Ruthenium-Lipase Couple

We report the dynamic kinetic resolution (DKR) of various secondary alcohols by the combination of a ruthenium catalyst and an anionic surfactant-activated lipoprotein lipase. The DKR reactions performed under totally base-free conditions at room temperature provided the products of excellent enantiopurities (91-99% ee or greater) in high yields (92-99%). More importantly, the DKR of α-arylallyl alcohols was achieved for the first time with high yields (87-91%).

Merging Iron Catalysis and Biocatalysis—Iron Carbonyl Complexes as Efficient Hydrogen Autotransfer Catalysts in Dynamic Kinetic Resolutions

A dual catalytic iron/lipase system has been developed and applied in the dynamic kinetic resolution of benzylic and aliphatic secondary alcohols. A detailed study of the Kn?lker-type iron complexes demonstrated the hydrogen autotransfer of alcohols to proceed under mild reaction conditions and allowed the combination with the enzymatic resolution. Different racemic alcohols were efficiently converted to chiral acetates in good yields and with excellent enantioselectivities.