1732-66-7

Basic information

• Product Name: Bis(2,4,6-trimethylphenyl)phosphine
• Synonyms: Bis(2,4,6-trimethylphenyl)phosphine 97%
• CAS NO: 1732-66-7
• Molecular Formula: C₁₈H₂₃P
• Molecular Weight: 270
• Mol File: 1732-66-7.mol
• Article Data: 17

Chemical Properties

• Melting Point: 95-100°C
• Boiling Point: 140-160 °C(Press: 0.1 Torr)
• Appearance: /
• CAS DataBase Reference: Bis(2,4,6-trimethylphenyl)phosphine(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(2,4,6-trimethylphenyl)phosphine(1732-66-7)
• EPA Substance Registry System: Bis(2,4,6-trimethylphenyl)phosphine(1732-66-7)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 1732-66-7(Hazardous Substances Data)

Usage

Description

Bis(2,4,6-trimethylphenyl)phosphine is an organophosphorus compound characterized by its two trimethylphenyl groups attached to a central phosphorus atom. It is known for its unique chemical properties and reactivity, making it a valuable compound in various chemical reactions and applications.

Uses

Used in Chemical Synthesis:
Bis(2,4,6-trimethylphenyl)phosphine is used as a reagent for the synthesis of bis(2,4,6-trimethylphenyl)phosphorus chloride. Bis(2,4,6-trimethylphenyl)phosphine serves as an important intermediate in the production of various organophosphorus compounds, which find applications in different industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, bis(2,4,6-trimethylphenyl)phosphine is used as a key building block for the development of novel drugs. Its unique chemical properties allow it to form stable complexes with various biological targets, making it a promising candidate for the design of new therapeutic agents.
Used in Agrochemical Industry:
Bis(2,4,6-trimethylphenyl)phosphine is also utilized in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its reactivity and stability make it an ideal candidate for the development of new compounds with improved efficacy and reduced environmental impact.
Used in Materials Science:
In the field of materials science, bis(2,4,6-trimethylphenyl)phosphine is employed in the development of advanced materials with unique properties. Its ability to form stable complexes with various elements makes it a valuable component in the design of new materials with enhanced performance characteristics, such as improved thermal stability, mechanical strength, and electrical conductivity.

Upstream product

• 287945-30-6 PdP(C₆H₅)2C₂H₄P(C₆H₅)2PH(C₆H₂(CH₃)3)2Cl⁽¹⁺⁾*O₃SCF₃^(1-)=PdP₂(C₆H₅)4C₂H₄PH(C₆H₂(CH₃)3)2Cl(SO₃CF₃) 
• 2923-28-6 silver trifluoromethanesulfonate 
• 67950-05-4 bis(2,4,6-trimethylphenyl)chlorophosphine 
• 4028-63-1 iodomesitylene 
• 14683-12-6 tellurium 
• 474353-55-4 [NiBr(2,4,6-trimethylphenyl)(2,2'-bipyridine)] 
• 68357-98-2 mesitylphosphine 
• 2633-66-1 2-mesitylmagnesium bromide 
• 67-56-1 methanol 
• 51272-82-3 white phosphorous 
• 250717-55-6 [Pd(dppe)(Me)(PMes₂H)]OTf 
• 1271-28-9 nickelocene 
• 144776-49-8 (C₆H₂(CH₃)3)2P(H)S 
• 146128-77-0 H₂AlP(C₆H₂(CH₃)3)2(N(CH₃)3) 

Downstream Products

• 127690-37-3 di(mesityl)phosphine-chloro-gold(I) 
• 146128-77-0 H₂AlP(C₆H₂(CH₃)3)2(N(CH₃)3) 
• 287945-34-0 Pd(P(C₆H₅)2C₂H₄P(C₆H₅)2)(⁽¹³⁾CH₃)PH(C₆H₂(CH₃)3)2⁽¹⁺⁾*CF₃SO₃^(1-)=Pd(P(C₆H₅)2C₂H₄P(C₆H₅)2)⁽¹³⁾CH₃PH(C₆H₂(CH₃)3)2(CF₃SO₃) 
• 287945-19-1 Pt(P(C₆H₅)2C₂H₄P(C₆H₅)2)(CH₃)PH(C₆H₂(CH₃)3)2⁽¹⁺⁾*CF₃SO₃^(1-)=Pt(P(C₆H₅)2C₂H₄P(C₆H₅)2)CH₃PH(C₆H₂(CH₃)3)2(CF₃SO₃) 
• 250717-55-6 [Pd(dppe)(Me)(PMes₂H)]OTf 
• 250717-56-7 [Pd(dppe)(Ph)(PMes₂H)](tetrafluoroborate) 
• 189826-52-6 Pt((C₆H₅)2PCH₂CH₂P(C₆H₅)2)P((CH₃)3C₆H₂)2(CH₃) 
• 189826-63-9 Pt(((C₆H₅)2PCH₂)2)(CH₃)(CHCNCH₂P(C₆H₂(CH₃)3)2) 
• 500735-48-8 cis-bis(dimesitylphosphine)dimethylpalladium(II) 
• 287945-25-9 PtP(C₆H₅)2C₂H₄P(C₆H₅)2PH(C₆H₂(CH₃)3)(CH₂C₆H₂(CH₃)2)⁽¹⁺⁾*CF₃SO₃^(1-) 
• 287945-23-7 PdP(C₆H₅)2C₂H₄P(C₆H₅)2PH(C₆H₂(CH₃)3)(CH₂C₆H₂(CH₃)2)⁽¹⁺⁾*CF₃SO₃^(1-) 
• 6781-97-1 (2,4,6-trimethylphenyl)phosphinic acid 
• 223758-68-7 1,4-bis(dimesitylphosphino)-2,3,5,6-tetrafluorobenzene 
• 222971-61-1 (R)-1-[Bis-(2-methoxy-phenyl)-phosphanyl]-3-[bis-(2,4,6-trimethyl-phenyl)-phosphanyl]-propan-2-ol 

Relevant articles and documents

Alkyne 1,1-Hydroboration to a Reactive Frustrated P/B-H Lewis Pair

The Mes2P-C≡C-SiMe3 alkyne reacts with the borane H2B-Fmes by means of a rare 1,1-hydroboration reaction to give an unsaturated C2-bridged frustrated P/B-H Lewis pair. Most of its reactions are determined by the presence of the B-H functionality at the FLP function and the activated connecting carbon-carbon double bond. It reduces carbon monoxide to the formyl stage. With nitriles it reacts in an extraordinary way: it undergoes a reaction sequence that eventually results in the formation of a P-substituted dihydro-1,2-azaborole derivative. Several similar examples were found. In one case a P-ylide was isolated that was related to an intermediate of the reaction sequence. It subsequently opened in an alternative way to give an alkenyl borane product.

Reactions of activated organonickel σ-complexes with elemental (white) phosphorus

The reactivity of organonickel σ-complexes of the type [NiBr(Ar)(bpy)] (Ar is 2,4,6-tri-methylphenyl (Mes) or 2,4,6-triisopropylphenyl (Tipp); bpy is 2,2′-bipyridine) toward elemental (white) phosphorus was studied. For the reaction to occur, the complexe

Photocatalytic Arylation of P4 and PH3: Reaction Development Through Mechanistic Insight

Detailed 31P{1H} NMR spectroscopic investigations provide deeper insight into the complex, multi-step mechanisms involved in the recently reported photocatalytic arylation of white phosphorus (P4). Specifically, these studies have identified a number of previously unrecognized side products, which arise from an unexpected non-innocent behavior of the commonly employed terminal reductant Et3N. The different rate of formation of these products explains discrepancies in the performance of the two most effective catalysts, [Ir(dtbbpy)(ppy)2][PF6] (dtbbpy=4,4′-di-tert-butyl-2,2′-bipyridine) and 3DPAFIPN. Inspired by the observation of PH3 as a minor intermediate, we have developed the first catalytic procedure for the arylation of this key industrial compound. Similar to P4 arylation, this method affords valuable triarylphosphines or tetraarylphosphonium salts depending on the steric profile of the aryl substituents.