173948-30-6

Basic information

• Product Name: (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine
• Synonyms: (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine
• CAS NO: 173948-30-6
• Molecular Weight: 217.354
• Mol File: 173948-30-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine(173948-30-6)
• EPA Substance Registry System: (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine(173948-30-6)

Safety Data

• Hazardous Substances Data: 173948-30-6(Hazardous Substances Data)

Usage

General Description

(E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine is a chemical compound with the molecular formula C17H27N. It is a tertiary amine and an alkene derivative, with a specific arrangement of isopropyl and phenyl groups attached to the amine nitrogen. (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine is commonly used as a ligand or catalyst in organic synthesis and chemical reactions. It may also be used as a building block in the preparation of various pharmaceutical and agrochemical compounds. Additionally, this chemical may have potential applications in medicinal chemistry and drug discovery due to its structural features and versatile reactivity. Overall, (E)-N,N-diisopropyl-3-phenylprop-2-en-1-amine has important roles in both research and industrial applications in the field of chemistry.

Upstream product

• 104-54-1 3-Phenylpropenol 
• 108-18-9 diisopropylamine 
• 300-57-2 allylbenzene 
• 1586-98-7 (2,3-dibromopropyl)benzene 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 2687-12-9 cinnamyl chloride 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Downstream Products

• 124936-74-9 N,N-diiso-propyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamine 
• 837376-36-0 3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropan-1-aminium bromide 
• 1333234-68-6 2-amino-2-(3-(3-(diisopropylamino)-1-phenylpropyl)-4-hydroxyphenyl)acetic acid 
• 207679-81-0 (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol 
• 250214-44-9 2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxyl-methyl)phenyl isobutyrate 
• 200801-70-3 RS-N,N-diisopropyl-3-(2-hydroxy-5-(hydroxymethyl)phenyl)-3-phenylpropylamine 
• 286930-02-7 fesoterodine 
• 286930-03-8 fesoterodine fumarate 
• 156755-20-3 PNU 200577 l-mandelate salt 
• 1333234-71-1 2-(3-(diisopropylamino)-1-phenylpropyl)-4-formylphenyl isobutyrate 
• 1587713-27-6 (Z)-N,N-diisopropyl-3-phenylprop-2-en-1-amine 
• 194482-44-5 Tolterodine acid 
• 124937-51-5 (R)-(+)-tolterodine 
• 1000377-72-9 C₃₁H₄₈N₂OSi 

Relevant articles and documents

Palladium-Catalyzed Allylic Amination of Allylic Alcohols with Tin(II) Chloride and Triethylamine

Allylic alcohols caused allylic amination with primary or secondary amines in the presence of a catalytic amount of Pd(PPh3)4 and stoichiometric amount of tin(II) chloride in THF at 50 deg C to produce the corresponding allylic amines regioselectively.

Practical regio- and stereoselective azidation and amination of terminal alkenes

There is significant interest in developing more rapid and efficient production of nitrogen-containing allylic compounds, as widely used in various syntheses. This work reports a variety of allylic azides and allylic amines synthesized by an efficient, new one-pot protocol that employs readily available terminal alkenes as starting materials. This method is highly regio- and stereoselective, affording the linear (E)-isomer, under metal-free conditions. This process tolerates several functional groups including halogen-containing molecules; it is general for azides and amine nucleophiles; and, adducts were obtained in good yields.

Anti-Markovnikov rearrangement in sulfur mediated allylic C-H amination of olefins

Cationic rearrangement reactions usually follow Markovnikov's rule to give more substituted carbocations as stable intermediates. During our study on sulfur mediated allylic C-H amination of olefins, very rare cases of anti-Markovnikov rearrangement from secondary carbocations toward primary carbocations or primary triflates were observed.