176317-02-5

Basic information

• Product Name: 2,3,4-Trifluorobromobenzene
• Synonyms: 1-BROMO-2,3,4-TRIFLUOROBENZENE;2,3,4-TRIFLUOROBROMOBENZENE;2,3,4-Trifluoro-1-bromobenzene;1-Bromo-2,3,4-trifluorobenzene, 97% 2,3,4-Trifluorobromobenzene];1-Bromo-2,3,4-trifluorobenzene 99%;1-Bromo-2,3,4-trifluorobenzene99%;2,3,4-Trifluorobromo;4-TrifluorobroMobenzene
• CAS NO: 176317-02-5
• Molecular Formula: C₆H₂BrF₃
• Molecular Weight: 210.98
• EINECS: -0
• Product Categories: Other fluorin-contained compounds;Fluorobenzene Series;Aromatic Halides (substituted);API intermediates;Miscellaneous;Benzenes;Fluorine series
• Mol File: 176317-02-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 47-47 °C (60 mmHg)
• Flash Point: 144 °F
• Appearance: Clear pale yellow liquid
• Density: 1.777 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.43mmHg at 25°C
• Refractive Index: n20/D 1.487(lit.)
• Storage Temp.: 2-8°C
• Water Solubility: Slightly soluble in water.
• BRN: 7805451
• CAS DataBase Reference: 2,3,4-Trifluorobromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-Trifluorobromobenzene(176317-02-5)
• EPA Substance Registry System: 2,3,4-Trifluorobromobenzene(176317-02-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39-36
• RIDADR: 1993
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 176317-02-5(Hazardous Substances Data)

Usage

Chemical Properties

Clear pale yellow liqui

Uses

1-Bromo-2,3,4-trifluorobenzene is used in synthesis of 5-nitro-6-methylquinoline carboxylic acid.

InChI:InChI=1/C6H2BrF3/c7-3-1-2-4(8)6(10)5(3)9/h1-2H

Upstream product

• 3862-73-5 2,3,4-trifluoroaniline 
• 1489-53-8 1,2,3-trifluorobenzene 

Downstream Products

• 193533-92-5 4-methyl-1,2,3-trifluorobenzene 
• 220987-81-5 1-bromo-4,5,6-trifluoro-2-[(4-methoxyphenyl)aminosulfonyl]benzene 
• 220987-80-4 1-Bromo-2,3,4-trifluoro-5-[(4-methoxyphenyl)aminosulfonyl]benzene 
• 459424-72-7 1-iodo-2,3,4-trifluorobenzene 
• 530145-56-3 (5-bromo-2,3,4-trifluorophenyl)triethylsilane 
• 212631-85-1 3-bromo-4,5,6-trifluorobenzoic acid 
• 705281-34-1 (2R,3S,5R)-2-Hydroxymethyl-5-(2,3,4-trifluoro-phenyl)-tetrahydro-furan-3-ol 
• 705281-28-3 (2R,3aS,9aR)-5,5,7,7-Tetraisopropyl-2-(2,3,4-trifluoro-phenyl)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacyclooctene 
• 705281-40-9 (2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,3,4-trifluoro-phenyl)-tetrahydro-furan-3-ol 
• 103557-21-7 1,1-bis(4-trifluoromethoxyphenyl)-2-(1,2,3,4-2H-tetrazol-2-yl)propan-1-ol 
• 819861-95-5 1-(3-methyl-3-hydroxy-1-butynyl)-2,3,4-trifluorobenzene 
• 1225651-74-0 ethyl 5-bromo-2,3,4-trifluorobenzoate 
• 1225650-99-6 (S)-1-methylheptyl 4-(4''-dodecyloxy-2,3,4-trifluoro-[1,1':4',1'']-terphenyl-5-ylcarbonyloxy)benzoate 
• 505058-38-8 3,3′,4,4′,5,5′-hexafluoro-1,1′-biphenyl 

Relevant articles and documents

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.

Novel 5-amino-6-methylquinolone antibacterials: A new class of non-6-fluoroquinolones

A novel 5-amino-6-methylquinoline carboxylic acid was synthesized from 2,3,4-trifluoro aniline in 12 steps and coupled with various types of amines to furnish new quinolone antibacterial agents. Depending on the structure of amine, some of quinolones showed comparable activity to ciprofloxacin or better Gram positive activity than ciprofloxacin, demonstrating that the C6 fluorine atom is not a necessary requirement for good antibacterial potency.