176327-49-4Relevant articles and documents
Antioxidant effects of the hydroxy groups in the simple phenolic carbazoles
Hieda, Yuhzo,Hatae, Noriyuki,Anraku, Makoto,Matsuura, Nobuyasu,Uemura, Kazuhide,Hibino, Satoshi,Choshi, Tominari,Tomida, Hisao,Hori, Osamu,Fujioka, Haruto
, p. 120 - 132 (2016/03/01)
Antioxidant activities of the simple phenolic carbazoles 5-11 were evaluated by 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulfonate)+ radical scavenging assays. The simple phenolic carbazoles 5-7, 9, and 11 exhibited stronger antioxidant activities than α-tocopherol, and similar antioxidant activities as phenolic carbazole alkaloids carazostatin (1), and carbazomadurins A (3) and B (4). Bond dissociation energies and highest occupied molecule orbital energy levels of a series of phenolic carbazoles including phenolic carbazole alkaloids were calculated. The reducing ability of the phenolic carbazole core could be important role for the antioxidant activity of carbazole alkaloids 1, 3, and 4.
Total synthesis of carazostatin and hyellazole by allene-mediated electrocyclic reaction
Choshi,Sada,Fujimoto,Nagayama,Sugino,Hibino
, p. 2593 - 2596 (2007/10/03)
The free radical scavenger carazostatin and the marine alkaloid hyellazole have been synthesized by a new type of allene-mediated electrocyclic reaction involving the indole 2,3-bond as a key step.
