17692-71-6

Basic information

• Product Name: Vanitiolide
• Synonyms: VANITIOLIDE;(4-HYDROXY-3-METHOXY-PHENYL)-MORPHOLIN-4-YL-METHANETHIONE;4-(thiovanilloyl)morpholine;4-(4-hydroxy-3-methoxyphenylthiocarbonyl)morpholine;CHEMBRDG-BB 5378542;4-[(4-Hydroxy-3-methoxyphenyl)thioxomethyl]morpholine
• CAS NO: 17692-71-6
• Molecular Formula: C₁₂H₁₅NO₃S
• Molecular Weight: 253.32
• EINECS: 241-690-5
• Mol File: 17692-71-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 411.31 °C at 760 mmHg
• Flash Point: 202.553 °C
• Appearance: /
• Density: 1.293 g/cm³
• Vapor Pressure: 2.21E-06mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: 2-8°C
• PKA: 9.25±0.31(Predicted)
• CAS DataBase Reference: Vanitiolide(CAS DataBase Reference)
• NIST Chemistry Reference: Vanitiolide(17692-71-6)
• EPA Substance Registry System: Vanitiolide(17692-71-6)

Safety Data

• Hazardous Substances Data: 17692-71-6(Hazardous Substances Data)

Usage

General Description

Vanitiolide is a naturally occurring chemical compound derived from the plant Centaurea scoparia. It is classified as a sesquiterpene lactone, a class of organic compounds with a specific three-ring molecular structure that are typically found in plants, fungi, and marine organisms. The molecule has demonstrated anti-inflammatory, antimicrobial, and cytotoxic properties in scientific studies, making it a potential candidate for pharmaceutical development. Its structural analysis has shown to exhibit a bicyclic guaiane type skeleton, making it unique in this particular category of compounds.

InChI:InChI=1/C12H15NO3S/c1-15-11-8-9(2-3-10(11)14)12(17)13-4-6-16-7-5-13/h2-3,8,17H,4-7H2,1H3/b12-9+

Upstream product

• 110-91-8 morpholine 
• 141-84-4 2-thioxo-4-thiazolidinone 
• 121-33-5 vanillin 

Relevant articles and documents

Cellulose-reinforced poly(ethylene-co-vinyl acetate)-supported Ag nanoparticles with excellent catalytic properties: Synthesis of thioamides using the Willgerodt-Kindler reaction

Cellulose, a bio-derived polymer, is widely used in food packaging, dye removal, coatings, and solidsupported catalysis. Heterogeneous catalysts play a critical role in environmental remediation. In this context, the demand for green and cost-effective catalysts has rapidly increased. In this study, cellulose was extracted from rice straw, and a highly active solid-supported catalytic model was developed. First, cellulose was conjugated with poly(ethylene-co-vinyl acetate) (PEVA), and then Ag nanoparticles (AgNPs) were inserted into the cellulose-PEVA composite. The process involved the reduction of AgNPs in the presence of sodium borohydride. The fabricated hybrid catalyst was characterized using Fouriertransform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray, and powder Xray diffraction. Thereafter, the obtained hybrid was used as a catalyst for the Willgerodt-Kindler reaction of aromatic aldehydes, amines, and S8 to synthesize thioamides with excellent yields. The developed catalytic system exhibited high stability and recyclability. Moreover, the mechanical properties of the hybrid catalyst were evaluated using tensile strength and impact tests. RGB analysis of digital images was also performed to investigate the primary components of the catalyst.