176963-05-6 Usage
Molecular structure
1H-Indole, 1-ethyl-7-methoxy-3-methyl-2-phenylis a complex molecule that contains an indole ring with various functional groups attached, including an ethyl, methoxy, methyl, and phenyl group.
Aromatic nature
The molecule's structure includes an indole ring, which is an aromatic system that contributes to its stability and potential medicinal properties.
Functional groups
The presence of various functional groups, such as the ethyl, methoxy, methyl, and phenyl groups, make the molecule versatile in organic synthesis and pharmaceutical research.
Biological activities
1H-Indole, 1-ethyl-7-methoxy-3-methyl-2-phenylhas potential biological activities that make it an interesting target for further investigation and potential applications in drug discovery and development.
Unique structure
The molecule's unique structure, with its complex indole system and various functional groups, makes it a promising building block for creating novel compounds with potential medicinal properties.
Check Digit Verification of cas no
The CAS Registry Mumber 176963-05-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,9,6 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 176963-05:
(8*1)+(7*7)+(6*6)+(5*9)+(4*6)+(3*3)+(2*0)+(1*5)=176
176 % 10 = 6
So 176963-05-6 is a valid CAS Registry Number.
176963-05-6Relevant articles and documents
Hydroxyindole derivatives as inhibitors of IL-1 generation. II. Synthesis and pharmacological activities of (E)3-(7-hydroxy-6-methoxyindole-4-yl)-2-methylpropenoic acid derivatives
Tanaka,Okita,Akamatsu,Chiba,Obaishi,Nagakura,Sakurai,Yamatsu
, p. 187 - 198 (2007/10/03)
A series of (E)-3-(7-hydroxy-6-methoxyindole-4-yl)-2-methylpropenoic acid derivatives was prepared and the inhibitory activities of its members on IL-1 generation were evaluated in an in vitro system using exudate cells from the rat carboxy-methyl cellulose (CMC) induced air-pouch model. All the compounds in this new series were found to be inhibitors of IL-1 generation. In particular, the methoxy-substituted 2-phenyl compounds 28d-f were the most potent inhibitors of IL-1 generation (eg, 28d: IC50 = 0.8 μ,M). The compounds in this series also inhibited IL-1α and IL-1β generations in an in vitro system using human monocytes stimulated with LPS (eg, 28b: IC50 = 1.4 μM (IL-1α) and 0.9 μM (IL-1β)).
