17698-09-8

Basic information

• Product Name: 2-(hydroxycarbamoyl)benzoic acid
• CAS NO: 17698-09-8
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.1455
• Mol File: 17698-09-8.mol
• Article Data: 7

Chemical Properties

• Density: 1.469g/cm³
• Refractive Index: 1.627
• CAS DataBase Reference: 2-(hydroxycarbamoyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(hydroxycarbamoyl)benzoic acid(17698-09-8)
• EPA Substance Registry System: 2-(hydroxycarbamoyl)benzoic acid(17698-09-8)

Safety Data

• Hazardous Substances Data: 17698-09-8(Hazardous Substances Data)

Usage

Class of organic compounds

Benzoic acids and derivatives 2-(hydroxycarbamoyl)benzoic acid belongs to a group of compounds that are derived from benzoic acid and have similar chemical properties.

Derivation

Combination of 2-amino-1,3-propanediol and 2-hydroxybenzoic acid The compound is formed by reacting these two starting materials, resulting in the formation of the desired product.

Physical appearance

White crystalline solid 2-(hydroxycarbamoyl)benzoic acid has a solid, crystalline structure with a white color.

Solubility

Sparingly soluble in water The compound does not dissolve easily in water, which may affect its behavior and applications in various processes.

Common use

Production of pharmaceuticals 2-(hydroxycarbamoyl)benzoic acid is often used in the synthesis of pharmaceutical compounds, particularly as an intermediate in the production of antineoplastic agents (anticancer drugs).

Specific application

Chelating agent in analytical chemistry The compound can bind to metal ions, making it useful as a chelating agent in analytical chemistry for tasks such as complexation, purification, and analysis of metal ions.

Chemical structure and properties

Versatile compound with various potential applications The unique structure and properties of 2-(hydroxycarbamoyl)benzoic acid make it a valuable compound for further research and development in different fields.

Upstream product

• 2306-33-4 monoethyl phthalate 
• 4376-18-5 Monomethyl phthalate 
• 524-38-9 N-hydroxyphthalimide 
• 64-17-5 ethanol 
• 85-44-9 phthalic anhydride 
• 17720-64-8 N-acetoxyphthalimide 
• 7732-18-5 water 
• 77-36-1 chlorthalidon 

Downstream Products

• 85-44-9 phthalic anhydride 
• 118-92-3 anthranilic acid 
• 7803-49-8 hydroxylamine 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 16653-19-3 N-(benzyloxy)phthalimide 
• 339106-00-2 2-(2,4-dichlorobenzyloxy)isoindole-1,3-dione 
• 34837-67-7 2-(phenylsulfonamido)benzoic acid 
• 100961-82-8 N-benzoyloxy-phthalamic acid 
• 17720-64-8 N-acetoxyphthalimide 
• 524-38-9 N-hydroxyphthalimide 

Relevant articles and documents

Hydroxamic acid rearrangement method for O-amino aromatic acid

The invention relates to the field of organic functional new material chemicals, and discloses a novel process technology for preparation of a hydroxamic acid precursor body weight discharge method of a plurality of o-amino aromatic acids in the first time. These substances are well known dyes and pigment and pharmaceutical pesticide-related fields and have a wide range of critical fine chemicals.

N-(benzyloxy)-2-chloronicotinamide compound as well as preparation method and application thereof

The invention belongs to the technical field of chemical synthesis and medicine application, and particularly relates to preparation and application of an N-(benzyloxy)-2-chloronicotinamide compound. The preparation method comprises the following steps: reacting phthalic anhydride with hydroxylamine, then reacting with triethylamine for acidification to prepare N-hydroxyphthalimide, then carrying out substitution and hydrazinolysis, and finally reacting with dichloronicotinoyl chloride to prepare the N-(benzyloxy)-2-chloronicotinamide compound. The preparation method disclosed by the invention is simple and convenient to operate, the structure of the obtained product is confirmed by a nuclear magnetic hydrogen spectrum, herbicidal activity tests are carried out on the obtained 15 target products, and results show that all target compounds have an obvious inhibition effect on the seeds of the Agrostis matsumurae under the concentration of 1mM, and the inhibition effect reaches 100%; and along with the decrease of the concentration, even if the concentration reaches 100 [mu] M, the target compound can still show good herbicidal activity.

PRODUCTION OF CYCLIC IMIDES SUITABLE FOR OXIDATION CATALYSIS

Disclosed are novel processes for the production of cyclic imide compounds such as N-hydroxyphthalimide (NHPI). The processes may be particularly well-suited for commercial-scale production of cyclic imides such as NHPI. Such cyclic imide compounds are suitable for use as oxidation catalysts, and specifically may be used to oxidize cyclohexylbenzene to cyclohexyl-1-phenyl-1-hydroperoxide. Such an oxidation may be particularly useful in a process for the production of phenol and/or cyclohexanone from benzene via a process comprising hydroalkylation of benzene to cyclohexylbenzene, oxidation of the cyclohexylbenzene to cyclohexyl-1-phenyl-1-hydroperoxide, and cleavage of the cyclohexyl-1-phenyl-1-hydroperoxide to phenol and cyclohexanone. The cyclic imide production process may advantageously include water washing and reactant recovery steps to maximize purity and yield.