177366-40-4

Basic information

• Product Name: (E)-4-Methyl-5-phenyl-pent-4-enoic acid [2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl]-amide
• Synonyms: (E)-4-Methyl-5-phenyl-pent-4-enoic acid [2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl]-amide
• CAS NO: 177366-40-4
• Molecular Weight: 513.75
• Mol File: 177366-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-Methyl-5-phenyl-pent-4-enoic acid [2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-Methyl-5-phenyl-pent-4-enoic acid [2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl]-amide(177366-40-4)
• EPA Substance Registry System: (E)-4-Methyl-5-phenyl-pent-4-enoic acid [2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl]-amide(177366-40-4)

Safety Data

• Hazardous Substances Data: 177366-40-4(Hazardous Substances Data)

Upstream product

• 177366-38-0 Methanesulfonic acid 2-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-ethyl ester 
• 177366-44-8 2-[1-Azido-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-ethyl-6-methoxy-5-methyl-pyran-4-one 
• 177366-43-7 2-[2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-3-ethyl-6-methoxy-5-methyl-pyran-4-one 
• 177366-31-3 6-(2-Benzyloxy-ethyl)-5-ethyl-4-hydroxy-3-methyl-pyran-2-one 
• 177366-32-4 2-(2-Benzyloxy-ethyl)-3-ethyl-6-methoxy-5-methyl-pyran-4-one 
• 177366-34-6 2-(1,2-Dihydroxy-ethyl)-3-ethyl-6-methoxy-5-methyl-pyran-4-one 
• 177366-33-5 3-Ethyl-6-methoxy-5-methyl-2-vinyl-pyran-4-one 
• 29304-40-3 2-methyl-3-oxohexanoic acid ethyl ester 
• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 83126-04-9 (4E)-4-methyl-5-phenylpent-4-enoic acid 
• 177366-39-1 2-[1-Amino-2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-ethyl-6-methoxy-5-methyl-pyran-4-one 

Downstream Products

• 177366-41-5 3-Ethyl-6-methoxy-5-methyl-2-[2-((E)-3-methyl-4-phenyl-but-3-enyl)-4,5-dihydro-oxazol-4-yl]-pyran-4-one 
• 134332-63-1 Phenoxan 
• 1027322-60-6 (E)-4-Methyl-5-phenyl-pent-4-enoic acid [1-(3-ethyl-6-methoxy-5-methyl-4-oxo-4H-pyran-2-yl)-2-hydroxy-ethyl]-amide 

Relevant articles and documents

Total synthesis of phenoxan and a related pyrone derivative

Phenoxan, HIV-1 inhibitor isolated from the myxobacteria, has been synthesized in 16 steps starting from ethyl 2-methylacetoacetate. The related isomer corresponding to the oxazole part was also obtained via an orthoester-enediol rearrangement.