17861-06-2

Basic information

• Product Name: 6-ETHOXYPURINE
• Synonyms: 6-ETHOXYPURINE;6-ethoxy-1h-purin;6-ethoxy-purin;6-ethoxy-1H-purine;6-ETHOXY-2-BROMONAPHTHALENE;6-Ethoxy-9H-purine;6-Ethoxy-7H-purine
• CAS NO: 17861-06-2
• Molecular Formula: C₇H₈N₄O
• Molecular Weight: 164.16
• EINECS: 241-813-2
• Product Categories: Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
• Mol File: 17861-06-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 427.6 °C at 760 mmHg
• Flash Point: 154.2 °C
• Appearance: /
• Density: 1.345 g/cm³
• CAS DataBase Reference: 6-ETHOXYPURINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ETHOXYPURINE(17861-06-2)
• EPA Substance Registry System: 6-ETHOXYPURINE(17861-06-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• RTECS: UO8530000
• Hazardous Substances Data: 17861-06-2(Hazardous Substances Data)

Usage

General Description

6-Ethoxypurine is a chemical compound which consists of a purine ring with an ethoxy functional group attached at the sixth position. It is derived from purine and has potential use as a pharmaceutical intermediate. It is also used in the research and development of new drugs, as purine derivatives have shown promise in treating various medical conditions such as cancer, gout, and neurological disorders. Additionally, 6-ethoxypurine is known to exhibit some antioxidant and anti-inflammatory properties, which may also make it useful in the development of new medications for related conditions. However, further research is needed to fully understand its potential applications in medicine.

InChI:InChI=1S/C7H8N4O/c1-2-12-7-5-6(9-3-8-5)10-4-11-7/h3-4H,2H2,1H3,(H,8,9,10,11)

Upstream product

• 141-52-6 sodium ethanolate 
• 87-42-3 6-chloro-7H-purine 
• 4316-98-7 6-chloro-4,5-diaminopyrimidine 
• 64-17-5 ethanol 
• 68-12-2 N,N-dimethyl-formamide 
• 87-42-3 6-chloropurine 

Downstream Products

• 220252-50-6 9-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-6-ethoxy-9H-purine 
• 220252-60-8 7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-6-ethoxy-7H-purine 

Relevant articles and documents

An efficient synthesis of substituted cytosines and purines under focused microwave irradiation

A rapid nucleophilic displacement reaction of 6-chloropurine, 2-amino-6-chloropurine and 5-bromocytosine with various nucleophiles under focused microwave irradiation is described. Using this method, the desired products were obtained with the yields up to 99% in?a?short reaction time.

N7-DNA: Base-pairing properties of N7-(2'-deoxy-β-d-erythro- pentofuranosyl)-substituted adenine, hypoxanthine, and guanine in duplexes with parallel chain orientation

Oligonucleotides containing N7-(2'-deoxy-β-D-erythro- pentofuranosyl)adenine (1), -hypoxanthine (2), and -guanine (3) were synthesized on solid-phase using phosphonate and phosphoramidite chemistry. As part of the synthesis of compound 2, the nucleobase-anion glycosylation of various 6-alkoxypurines with 2-deoxy-3,5-di-O-(4-toluoyl)-α-D-erythro- pentofuranosyl chloride (5) was investigated. The duplex stability of oligonucleotides containing N7-glycosylated purines opposite to regular pyrimidines was determined, and thermodynamic data were calculated from melting profiles. Oligodeoxyribonucleotide duplexes containing N7- glycosylated adenine. T(d) or N7-glycosylated guanine C(d) base pairs are more stable in the case of parallel strand orientation than in the case of antiparallel chains.