178869-03-9

Basic information

• Product Name: 2,6-diphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane
• Synonyms: 2,6-diphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane
• CAS NO: 178869-03-9
• Molecular Weight: 254.288
• Mol File: 178869-03-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-diphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-diphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane(178869-03-9)
• EPA Substance Registry System: 2,6-diphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane(178869-03-9)

Safety Data

• Hazardous Substances Data: 178869-03-9(Hazardous Substances Data)

Upstream product

• 586-96-9 Nitrosobenzene 
• 121767-19-9 1-Phenyl-2-aza-3-trimethylsilyloxy-1,3-butadiene 

Downstream Products

• 21969-70-0 2-anilinoacetamide 

Relevant articles and documents

Electrophilic amination of 2-azadienes

2-Azadienes 1 bearing a trialkylsilyloxy group on position 3 can be regarded as carboxylic acid synthons. Their cycloadditions with several classes of nitroso compounds have been studied in detail as well as the transformation of the adducts into α-amino acids. The study showed that arylnitroso compounds such as nitrosobenzene reacted with 2-azadienes to give adducts that are potential precursors of α-N-arylamino acids. We have outlined an important limitation to the use of α-chloronitroso compounds. They are not compatible with highly functionalized dienes like 2-azadienes. On the other hand α-cyanonitroso and acylnitroso compounds reacted with azadienes to give adducts which were readily converted into α-amino acid derivatives.