179057-14-8

Basic information

• Product Name: Methyl 4-(5-Oxazolyl)benzoate
• Synonyms: Methyl 4-(5-Oxazolyl)benzoate;methyl 4-(oxazol-5-yl)benzoate;5-[4-(Methoxycarbonyl)phenyl]-1,3-oxazole
• CAS NO: 179057-14-8
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203
• Mol File: 179057-14-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 112～114℃
• Boiling Point: 341.5°C at 760 mmHg
• Flash Point: 160.4°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 7.99E-05mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: Methyl 4-(5-Oxazolyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-(5-Oxazolyl)benzoate(179057-14-8)
• EPA Substance Registry System: Methyl 4-(5-Oxazolyl)benzoate(179057-14-8)

Safety Data

• Hazardous Substances Data: 179057-14-8(Hazardous Substances Data)

Usage

General Description

Methyl 4-(5-oxazolyl)benzoate is a chemical compound with the molecular formula C11H9NO3. It is a derivative of benzoic acid and contains a methyl ester group as well as an oxazole ring. The compound is commonly used in the fragrance and flavoring industry due to its pleasant odor and taste. It may also have potential applications in the pharmaceutical industry, as oxazole derivatives have been studied for their potential biological activities. Additionally, it is important to handle this compound with care as it may pose certain health risks if mishandled or exposed to inappropriately. Overall, Methyl 4-(5-oxazolyl)benzoate is a versatile chemical with various potential applications.

InChI:InChI=1/C11H9NO3/c1-14-11(13)9-4-2-8(3-5-9)10-6-12-7-15-10/h2-7H,1H3

Upstream product

• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 1571-08-0 methyl 4-formylbenzoate 
• 29166-72-1 N,N,N′,N′-tetramethyl-N″-tert-butylguanidine 

Downstream Products

• 250161-45-6 4-(1,3-oxazol-5-yl)benzoic acid 
• 1264661-10-0 methyl 4-[2-{2-(pyridin-2-yl)phenyl}oxazol-5-yl]benzoate 
• 179055-60-8 Cycloheptyl-(4-oxazol-5-yl-benzyl)-amine 
• 179057-31-9 4-(oxazol-5-yl)benzaldehyde 
• 179057-18-2 [4-(1,3-oxazol-5-yl)phenyl]methanol 

Relevant articles and documents

Ring size changes in the development of class I HDAC inhibitors

Five pathways involving different ring structures led to generation of fourteen thienylbenzamides (7–20) which display the structure-activity relationships of class I HDAC inhibitors. All the synthesised compounds inhibit HDAC1 and HDAC2 selectively over other isoforms and many inhibit DLD1 and HCT116 cells more effectively than a parent compound. Compounds 8 and 16 inhibit HCT116 cells by activation of the apoptosis pathway.

Copper-mediated dehydrogenative biaryl coupling of naphthylamines and 1,3-azoles

A copper-mediated dehydrogenative biaryl cross-coupling of naphthylamines and 1,3-azoles has been developed. The key to its success is the introduction of N,N-bidentate coordination system based on the picolinamide directing group. The reaction proceeds s

DIAGNOSTIC AND REMEDY FOR DISEASE CAUSED BY AMYLOID AGGREGATION AND/OR DEPOSITION

To provide a diagnostic drug which binds specifically to an amyloid aggregate and/or an amyloid deposit, to thereby realize imaging and quantification of a disease caused by amyloid aggregation and/or deposition. The invention provides a compound represented by formula (1) : (wherein X1 represents an optionally substituted bicyclic heterocyclic group; X2 represents a hydrogen atom, a halogen atom, or a chelate-forming group; ring A represents a benzene ring or a pyridine ring; and ring B represents an optionally substituted 5-membered aromatic heterocyclic group which is bonded to the benzene ring or the pyridine ring via a carbon atom of ring B), a salt thereof, a solvate of any of these, or a transition metal coordination compound of any of these, and a diagnostic, preventive, or therapeutic drug containing the same.