179115-17-4Relevant articles and documents
PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE
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Paragraph 0177; 0211, (2021/05/07)
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
Paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity
Schultz, Christiane,Link, Andreas,Leost, Maryse,Zaharevitz, Daniel W.,Gussio, Rick,Sausville, Edward A.,Meijer, Laurent,Kunick, Conrad
, p. 2909 - 2919 (2007/10/03)
The paullones represent a novel class of small molecule cyclin-dependent kinase (CDK) inhibitors. To investigate structure-activity relationships and to develop paullones with antitumor activity, derivatives of the lead structure kenpaullone (9-bromo-7,12