179386-44-8 Usage
Description
(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate is a complex organic compound with a unique chemical structure. It is characterized by its imidazoquinolinone core, which is fused with a quinoline ring and features a methylamino group at the 5-position. The compound is further characterized by its (Z)-2-butenedioate group, which is a dicarboxylate moiety that can potentially engage in various chemical interactions. This molecule's structure suggests it may have applications in medicinal chemistry, particularly as a precursor or building block for the development of pharmaceuticals targeting specific receptors or enzymes.
Uses
Used in Pharmaceutical Industry:
(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a promising candidate for the development of new drugs targeting specific receptors or enzymes, potentially leading to treatments for a range of diseases and conditions.
Used in Research and Development:
In the field of research and development, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate can be utilized as a starting material or a probe to investigate the structure-activity relationships of various biologically active molecules. Its synthesis and modification can provide valuable insights into the design and optimization of novel therapeutic agents.
Used in Drug Design and Optimization:
The compound can be employed in drug design and optimization processes, where its unique structural features and functional groups can be exploited to improve the potency, selectivity, and pharmacokinetic properties of drug candidates. This may involve the development of new drugs for the treatment of neurological disorders, such as Parkinson's disease, by targeting specific dopamine receptor subtypes, as demonstrated by the example of Sumanirole, a high affinity D2 receptor agonist with antiParkinsonian activity.
Biochem/physiol Actions
Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.
Check Digit Verification of cas no
The CAS Registry Mumber 179386-44-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,3,8 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 179386-44:
(8*1)+(7*7)+(6*9)+(5*3)+(4*8)+(3*6)+(2*4)+(1*4)=188
188 % 10 = 8
So 179386-44-8 is a valid CAS Registry Number.
179386-44-8Relevant articles and documents
Sustained release tablet formulation to treat Parkinson's disease
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, (2008/06/13)
The sustained release tablet of (R)-5,6-dihydro-5-(methylamino)-4H-imidazo[4,5-ij]-quinolin-2(1H)-one (Z)-2-butenedioate (1:1) which is disclosed permits twice daily administration of (R)-5,6-dihydro-5-(methylamino)-4H-imidazo[4,5-ij]-quinolin-2(1H)-one (
