179556-80-0

Basic information

• Product Name: (5-Amino-1H-indol-2-yl)-{4-[(3-ethoxy-pyridin-2-yl)-methyl-amino]-piperidin-1-yl}-methanone
• CAS NO: 179556-80-0
• Molecular Weight: 393.489
• Mol File: 179556-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5-Amino-1H-indol-2-yl)-{4-[(3-ethoxy-pyridin-2-yl)-methyl-amino]-piperidin-1-yl}-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Amino-1H-indol-2-yl)-{4-[(3-ethoxy-pyridin-2-yl)-methyl-amino]-piperidin-1-yl}-methanone(179556-80-0)
• EPA Substance Registry System: (5-Amino-1H-indol-2-yl)-{4-[(3-ethoxy-pyridin-2-yl)-methyl-amino]-piperidin-1-yl}-methanone(179556-80-0)

Safety Data

• Hazardous Substances Data: 179556-80-0(Hazardous Substances Data)

Upstream product

• 170856-57-2 N-(1-benzylpiperidin-4-yl)-N-(3-ethoxypyridin-2-yl)-methylamine 
• 170856-58-3 N-(piperidin-4-yl)-N-(3-ethoxypyridin-2-yl)methylamine 
• 16730-20-4 5-nitro-1H-indole-2-carboxylic acid 
• 89694-54-2 2-bromo-3-ethoxypyridine 
• 6602-32-0 2-bromo-pyridin-3-ol 
• 179556-79-7 {4-[(3-Ethoxy-pyridin-2-yl)-methyl-amino]-piperidin-1-yl}-(5-nitro-1H-indol-2-yl)-methanone 

Relevant articles and documents

Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: Structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs

The major route of metabolism of the bis(heteroaryl)piperazine (BHAP) class of reverse transcriptase inhibitors (RTIs), atevirdine and delavirdine, is via oxidative N-dealkylation of the 3-ethyl- or 3-isopropylamino substituent on the pyridine ring. This