1802323-89-2 Usage
Description
Prasterone trifluoroacetate triflate, also known as Abiraterone Impurity 8, is a chemical compound derived from prasterone, a steroidal hormone. It is characterized by its unique molecular structure, which includes a trifluoromethylsulfonyloxy group and a trifluoroacetate group. prasterone trifluoroacetate triflate is an impurity found in Abiraterone (Abiraterone Impurity 8), a drug that inhibits the enzyme CYP17 and is currently in phase II clinical trials for the treatment of androgen-dependent prostate cancer.
Uses
Used in Pharmaceutical Industry:
Prasterone trifluoroacetate triflate is used as an impurity in the development and production of Abiraterone, a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17). Its presence in the drug is crucial for understanding the potential side effects and interactions that may occur during the treatment of androgen-dependent prostate cancer.
Used in Clinical Trials:
In the context of phase II clinical trials, prasterone trifluoroacetate triflate serves as a reference compound to evaluate the safety, efficacy, and pharmacokinetics of Abiraterone. By studying the effects of this impurity, researchers can gain insights into the overall performance of the drug and make necessary adjustments to improve its therapeutic potential.
Used in Research and Development:
Prasterone trifluoroacetate triflate is also utilized in research and development efforts to explore its potential applications beyond its role as an impurity in Abiraterone. Scientists may investigate its chemical properties, interactions with other compounds, and possible uses in the development of new drugs or therapies for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1802323-89-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,2,3,2 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1802323-89:
(9*1)+(8*8)+(7*0)+(6*2)+(5*3)+(4*2)+(3*3)+(2*8)+(1*9)=142
142 % 10 = 2
So 1802323-89-2 is a valid CAS Registry Number.
1802323-89-2Relevant articles and documents
PROCEDURE FOR THE PREPARATION OF ABIRATERONE ACETATE AND INTERMEDIATES THEREOF
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Page/Page column 13, (2015/09/23)
Disclosed is a process for the preparation of abiraterone and abiraterone acetate with high yields and purity. A key element of the method is the isolation of a crystalline intermediate that makes the process particularly suitable for implementation on an industrial scale.
