180304-16-9

Basic information

• Product Name: ethyl 4-(2-azidoethoxy)-3-methoxyphenylacetate
• CAS NO: 180304-16-9
• Molecular Weight: 279.296
• Mol File: 180304-16-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 4-(2-azidoethoxy)-3-methoxyphenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(2-azidoethoxy)-3-methoxyphenylacetate(180304-16-9)
• EPA Substance Registry System: ethyl 4-(2-azidoethoxy)-3-methoxyphenylacetate(180304-16-9)

Safety Data

• Hazardous Substances Data: 180304-16-9(Hazardous Substances Data)

Upstream product

• 60563-13-5 ethyl homovanillate 
• 306-08-1 Homovanillic acid 
• 1369499-18-2 C₁₃H₁₇ClO₄ 

Downstream Products

• 1391848-25-1 C₁₂H₁₅N₃O₄ 
• 1391848-20-6 C₂₃H₃₂N₂O₃ 
• 1391847-93-0 C₂₃H₃₀N₄O₃ 
• 1391847-94-1 C₂₃H₃₂N₂O₃ 
• 1391848-33-1 C₂₃H₃₀N₄O₃ 
• 1391848-30-8 C₁₄H₁₉N₃O₄ 

Relevant articles and documents

The SAR analysis of TRPV1 agonists with the α-methylated B-region

A series of TRPV1 agonists with amide, reverse amide, and thiourea groups in the B-region and their corresponding α-methylated analogues were investigated. Whereas the α-methylation of the amide B-region enhanced the binding affinities and potencies as agonists, that of the reverse amide and thiourea led to a reduction in receptor affinity. The analysis indicated that proper hydrogen bonding as well as steric effects in the B-region are critical for receptor binding.