180348-04-3Relevant articles and documents
Enantioselective fluorination of α-branched aldehydes and subsequent conversion to α-hydroxyacetals via stereospecific C-F bond cleavage
Shibatomi, Kazutaka,Kitahara, Kazumasa,Okimi, Takuya,Abe, Yoshiyuki,Iwasa, Seiji
, p. 1388 - 1392 (2016/02/05)
The highly enantioselective fluorination of α-branched aldehydes was achieved using newly developed chiral primary amine catalyst 1. Furthermore, the C-F bond cleavage of the resulting α-fluoroaldehydes proceeded smoothly under alcoholic alkaline conditio
New synthetic routes to 2-fluoro-2-phenylalkanoic acids
Goj, Olav,Haufe, Guenter
, p. 1289 - 1294 (2007/10/03)
2-Fluoro-2-phenylalkanoic acids 2 are obtained by oxidation of the corresponding β-fluoro-β-phenyl alcohols 6. These compounds are shown to be accessible by two alternative pathways, either by bromo fluorination of α-alkyl styrenes 3, subsequent bromine-b
