180464-92-0

Basic information

• Product Name: Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI)
• Synonyms: Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI);methyl 3-formylbicyclo[1.1.1]pentane-1-carboxylate;Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester
• CAS NO: 180464-92-0
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 154.1632
• Product Categories: ALDEHYDE;CARBOXYLICESTER
• Mol File: 180464-92-0.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI)(180464-92-0)
• EPA Substance Registry System: Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI)(180464-92-0)

Safety Data

• Hazardous Substances Data: 180464-92-0(Hazardous Substances Data)

Usage

General Description

Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9CI) is a chemical compound with a molecular formula of C8H10O2. It is a methyl ester derivative of bicyclo[1.1.1]pentane-1-carboxylic acid, which is a bicyclic compound. This chemical is primarily used in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. It is also employed in the field of medicinal chemistry for the development of new drug candidates. The compound's unique structure and reactivity make it a valuable building block for the creation of complex organic molecules. However, it is important to handle and use this chemical with caution due to its potential hazards and toxicological properties.

Upstream product

• 311-75-1 bicyclo[1.1.1]pentane 
• 180464-87-3 methyl 3-(hydroxylmethyl)bicyclo[1.1.1]pentane-1-carboxylate 
• 56842-95-6 bicyclo<1.1.1>pentane-1,3-dicarboxylic acid 
• 115913-32-1 dimethyl bicyclo<1.1.1>pentane-1,3-dicarboxylate 
• 115913-31-0 1,3-bis(chlorocarbonyl)bicyclo<1.1.1>pentane 
• 83249-10-9 3‐(methoxycarbonyl)bicyclo[1.1.1]pentane‐1‐carboxylic acid 
• 115913-30-9 1,1′-(bicyclo[1.1.1]pentane-1,3-diyl)bis(ethan-1-one) 

Downstream Products

• 180464-96-4 3-[(S)-Cyano-((R)-2-hydroxy-1-phenyl-ethylamino)-methyl]-bicyclo[1.1.1]pentane-1-carboxylic acid methyl ester 
• 180465-00-3 3-[(R)-Cyano-((R)-2-hydroxy-1-phenyl-ethylamino)-methyl]-bicyclo[1.1.1]pentane-1-carboxylic acid methyl ester 

Relevant articles and documents

TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE

The present disclosure relates to bifunctional compounds, which find utility as modulators of tan protein. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a VHL or cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds tan protein, such that tan protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of tan. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of tan protein. Diseases or disorders that result from aggregation or accumulation of tan protein are treated or prevented with compounds and compositions of the present disclosure.

INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE

The present invention provides a compound represented by formula [I] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme. (in formula [I] above, the structure represented by formula [II] below: represents any of the structures represented by formula group [III] below: R1, R2, R3, and R4 independently represent a hydrogen atom, a fluorine atom, methyl, or the like, R5 represents any of the structures represented by formula group [IV]: