180994-87-0

Basic information

• Product Name: 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile
• Synonyms: 2-Amino-3-cyano-4-methyl-5-bromopyridine;2-Amino-5-bromo-3-cyano-4-picoline;2-AMino-5-broMo-4-Methyl-nicotinonitrile;2-amino-5-bromo-4-methyl-3-Pyridinecarbonitrile;3-Pyridinecarbonitrile, 2-amino-5-bromo-4-methyl-
• CAS NO: 180994-87-0
• Molecular Formula: C₇H₆BrN₃
• Molecular Weight: 212.05
• Product Categories: Pyridine
• Mol File: 180994-87-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 303.5 °C at 760 mmHg
• Flash Point: 137.4 °C
• Appearance: /
• Density: 1.68 g/cm³
• Vapor Pressure: 0.000924mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile(180994-87-0)
• EPA Substance Registry System: 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile(180994-87-0)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 180994-87-0(Hazardous Substances Data)

Usage

Description

2-Amino-5-bromo-4-methylpyridine-3-carbonitrile, also known as ABMP3CN, is a chemical compound characterized by a pyridine ring with a bromine and a methyl group attached, along with an amino and carbonitrile functional groups. It is recognized for its versatility as a building block in organic chemistry, particularly in the synthesis of pharmaceuticals and agrochemicals, and is valued for its unique structure and reactivity in the field of chemical synthesis and drug development.

Uses

Used in Pharmaceutical Industry:
2-Amino-5-bromo-4-methylpyridine-3-carbonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties. Its presence in the molecular structure can influence the pharmacokinetics and pharmacodynamics of the final drug product.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides, where its chemical properties can enhance the effectiveness and selectivity of these compounds in agricultural applications.
Used in Organic Chemistry Research:
ABMP3CN is employed as a research compound in organic chemistry to explore novel reactions and mechanisms, contributing to the advancement of synthetic methodologies and the discovery of new chemical entities with potential applications in various industries.

InChI:InChI=1/C7H6BrN3/c1-4-5(2-9)7(10)11-3-6(4)8/h3H,1H3,(H2,10,11)

Upstream product

• 71493-76-0 2-amino-4-methylpyridine-3-carbonitrile 
• 410547-37-4 4,4-dicyano-3-methyl-3-butenal dimethyl acetal 

Downstream Products

• 180994-88-1 2-amino-3-cyano-4-methyl-5-[3,5-di(trifluoromethyl)phenyl]pyridine 
• 72732-56-0 piritrexim 
• 153944-51-5 2-bromo-3-cyano-4-methyl-5-(2,5-dimethoxybenzyl)pyridine 
• 847234-66-6 2-amino-3-cyano-4-methyl-5-(2,5-dimethoxybenzyl)pyridine 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

2,4-diamino-5,6-disubstituted- and 5,6,7-trisubstituted 5-deazapteridines as insecticides

An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a 5-deazapteridine compound of the formula: STR1 wherein R1, R2, R3, R4, U, V, and W are as defined herein; agriculturally acceptable salts thereof; methods for using the same; and certain novel 5-deazapteridines per se.