181308-89-4

Basic information

• Product Name: Ethanone, 1-(4-methoxyphenyl)-2-[4-(trifluoromethyl)phenyl]-
• CAS NO: 181308-89-4
• Molecular Formula: C16H13F3O2
• Molecular Weight: 294.273
• Mol File: 181308-89-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-methoxyphenyl)-2-[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-methoxyphenyl)-2-[4-(trifluoromethyl)phenyl]-(181308-89-4)
• EPA Substance Registry System: Ethanone, 1-(4-methoxyphenyl)-2-[4-(trifluoromethyl)phenyl]-(181308-89-4)

Safety Data

• Hazardous Substances Data: 181308-89-4(Hazardous Substances Data)

Upstream product

• 40474-01-9 1-methoxy-4-((4-(trifluoromethyl)phenyl)ethynyl)benzene 
• 32857-62-8 4-Trifluoromethylphenylacetic acid 
• 100-66-3 methoxybenzene 
• 794-94-5 p-Methoxybenzoic anhydride 
• 74426-51-0 4-(trifluoromethyl)phenylacetyl chloride 

Downstream Products

• 6185-76-8 (4-methoxyphenyl)(4-(trifluoromethyl)phenyl)methanone 
• 455-24-3 4-trifluoromethylbenzoic acid 
• 100-09-4 4-methoxybenzoic acid 

Relevant articles and documents

Synthesis of substituted phenanthrofurans

A three-step protocol toward phenanthrofurans 1 starting with deoxybenzoins 3 is developed with moderate to good yield. A facile process is carried out for the (1) α-propargylation of 3 with NaH and propargyl bromide 2 in refluxing THF, (2) Bi(OTf)3-mediated cycloisomerization of γ-ynones 4 with 4 ? molecular sieves in MeNO2 at rt, and (3) photolytic Scholl annulation of 2,3-diarylfurans 5 with I2 in EtOAc at rt. The key structures of 1 are confirmed by X-ray crystallographic analysis.

Diversity in platinum-catalyzed hydrative cyclization of trialkyne substrates to form tetracyclic ketones

(Chemical Equation Presented) We report a one-pot synthesis of tetracyclic ketones via PtI2-catalyzed hydrative cyclization of trialkyne functionalities. These triyne substrates bear an electron-rich aryl group at the outer alkyne to direct the

Palladium-Catalyzed Cross-Coupling Reactions of Carboxylic Anhydrides with Organozinc Reagents

(Matrix presented) Negishi-type cross-coupling reaction was effected by employing organozincs and anhydrides or mixed anhydrides that formed in situ from sodium salts of the corresponding acids and ethyl chloroformate under the catalysis of palladium(0). A general method for preparing symmetrical/ unsymmetrical ketones was developed.