1817-28-3 Usage
Physical state
Colorless liquid
Odor
Characteristic
Common uses
Solvent in industrial processes
Solubility
High in water
Ability
Dissolves a wide range of organic and inorganic substances
Application
Intermediate in the synthesis of pharmaceuticals and agrochemicals
Utilization
Production of plastics, polymers, and other materials
Toxicity
Not known to be highly toxic
Environmental impact
Not harmful to the environment
Handling precautions
Handle with care
Storage conditions
Cool, dry place
Check Digit Verification of cas no
The CAS Registry Mumber 1817-28-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1817-28:
(6*1)+(5*8)+(4*1)+(3*7)+(2*2)+(1*8)=83
83 % 10 = 3
So 1817-28-3 is a valid CAS Registry Number.
1817-28-3Relevant articles and documents
Carbon-Carbon Bond Formation of Trifluoroacetyl Amides with Grignard Reagents via C(O)-CF3 Bond Cleavage
Zhu, Longzhi,Le, Liyuan,Yan, Mingpan,Au, Chak-Tong,Qiu, Renhua,Kambe, Nobuaki
, p. 5635 - 5644 (2019/05/10)
The reaction of trifluoroacetyl amides with Grignard reagent for the substitution of CF3 group with various alkyl or aryl groups is described. A variety of aryl, quinolin-8-yl, and (hetero)alkyl functional groups as well as F, Cl, and Br atoms are well tolerated. These moisture-stable and easily available trifluoroacetyl amides can be conveniently obtained and used as new versatile precursors for isocyanates. The control experiments show that the reaction proceeds via an isocyanate intermediate and/or alkoxide/amide dual anionic intermediate.
