18194-25-7 Usage
Description
DLPC, also known as 1,2-dilauroyl-sn-glycero-3-phosphocholine, is a phospholipid containing the 12 carbon fatty acid/lauric acid (12:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.
Uses
Different sources of media describe the Uses of 18194-25-7 differently. You can refer to the following data:
1. L-α-Dilauroyl Phosphatidylcholine forms robust and versatile membrane bilayers to study the selective and ATP-driven transport ions across membranes into nanoporous carriers using gramicidin A and AT
P synthase.
2. 1,2-Dilauroyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Experimentally, DLPC is used to form thinner membranes than those produced with PC containing the more common long-chain or very long-chain fatty acids, or to simply vary membrane formulation.
3. L-α-Dilauroyl Phosphatidylcholine forms robust and versatile membrane bilayers to study the selective and ATP-driven transport ions across membranes into nanoporous carriers using gramicidin A and ATP synthase.
Definition
ChEBI: A phosphatidylcholine 24:0 in which the acyl groups at positions 1 and 2 are specified as lauroyl (dodecanoyl).
Check Digit Verification of cas no
The CAS Registry Mumber 18194-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,9 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18194-25:
(7*1)+(6*8)+(5*1)+(4*9)+(3*4)+(2*2)+(1*5)=117
117 % 10 = 7
So 18194-25-7 is a valid CAS Registry Number.
InChI:InChI=1/C32H64NO8P.2H2O/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2;;/h30H,6-29H2,1-5H3;2*1H2/t30-;;/m1../s1
18194-25-7Relevant articles and documents
Method for producing liposomes with increased percent of compound encapsulated
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, (2008/06/13)
The efficiency of encapsulating a drug into a liposomal formulation is increased by use of a lipid having a carbon chain containing from about 13 to about 28 carbons during preparation of the liposomes. Preferably the liposomes are multivesicular liposomes.
