182268-32-2Relevant articles and documents
Asymmetric synthesis of new β-lactam lipopeptides as bacterial signal peptidase i inhibitors
Crauste, Celine,Froeyen, Matheus,Anne, Jozef,Herdewijn, Piet
, p. 3437 - 3449 (2011/09/12)
The transmembrane bacterial enzyme, signal peptidase I, is recognized as being a promising target for reducing the emergence of drug resistance. The asymmetric synthesis and the biological evaluation of original β-lactam lipopeptides have been performed t